| 19例儿童及青少年Evans综合征回顾性临床分析 |
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| 引用本文： | 董恂玮,赵玉平,郑以州,张凤奎,杨仁池.19例儿童及青少年Evans综合征回顾性临床分析[J].临床血液学杂志,2011(1):28-29,32. |
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| 作者姓名： | 董恂玮 赵玉平 郑以州 张凤奎 杨仁池 |
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| 作者单位： | 中国医学科学院北京协和医学院血液病医院(血液学研究所); |
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| 基金项目： | 公益性卫生行业科研专项基金(No:200802031) |
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| 摘 要： | 目的:评价联合治疗对儿童及青少年Evans综合征的疗效.方法:回顾性分析1984-2007年19例儿童及青少年Evans综合征患者的临床特征以及各种治疗方案的疗效.结果:19例患者中17例女性,2例男性,所有患者均给予标准或大剂量糖皮质激素作为一线治疗,完全缓解率达64.29%,中位随访24个月,88.89%患者复发....
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| 关 键 词： | Evans综合征 一线治疗 二线治疗 脾切除 免疫球蛋白 免疫失调 |
A retrospective study of 19 childhood and adolescent patients with Evans syndrome in a single center |
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| DONG Xunwei ZHAO Yuping ZHENG Yizhou ZHANG Fengkui YANG Renchi.A retrospective study of 19 childhood and adolescent patients with Evans syndrome in a single center[J].Journal of Clinical Hematology,2011(1):28-29,32. |
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| Authors: | DONG Xunwei ZHAO Yuping ZHENG Yizhou ZHANG Fengkui YANG Renchi |
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| Institution: | DONG Xunwei ZHAO Yuping ZHENG Yizhou ZHANG Fengkui YANG Renchi(State Key Laboratory of Experimental Hematology,Tianjin,300020,China) |
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| Abstract: | Objective:To evaluate the efficacy of combination treatments for childhood and adolescent patients with Evans syndrome.Method:In this retrospective study,we evaluated the clinical features and the effects of various treatment regimens on the clinical course of childhood and adolescent patients with Evans syndrome in our center between 1984-2007.Result:Nineteen (17 females,2 males) patients were included. All patients were treated with either standard or high-dose steroids as first line therapy. CR was achie... |
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| Keywords: | Evans syndrome first-line therapy second-line therapy splenectomy serum immunoglobulins immune dysregulation |
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