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| 地黄地上部分中一个新苯甲醛类化合物 | |
| 引用本文： | 邹妍,张蕾,续洁琨,程钱,叶贤胜,李平,张维库,李永吉.地黄地上部分中一个新苯甲醛类化合物[J].中国中药杂志,2015,40(7):1316-1319. |
| 作者姓名： | 邹妍 张蕾 续洁琨 程钱 叶贤胜 李平 张维库 李永吉 |
| 作者单位： | 1. 中日友好医院临床医学研究所药物药理室,北京100029;黑龙江中医药大学药学院,黑龙江哈尔滨150040 2. 中日友好医院临床医学研究所药物药理室,北京,100029 3. 北京中医药大学基础医学院,北京,100029 4. 北京中医药大学中药学院,北京,100029 5. 黑龙江中医药大学药学院,黑龙江哈尔滨,150040 |
| 基金项目： | 国家自然科学基金项目(81473119,81274115);中日友好医院青年科技英才项目(2014-QNYC-13-10);中日友好医院院内课题面上项目(2013-MS-34);北京市优秀人才培养资助项目(2013D009999000001) |
| 摘 要： | 运用各种色谱技术对玄参科地黄属植物地黄的地上部分进行分离纯化,从中分离得到7个化合物,根据理化性质和波谱数据分别鉴定为3-hydroxy-4-(4-(2-hydroxyethyl)phenoxy)benzaldehyde(1),异香草酸(isovanillic acid,2),邻苯二酚(pyrocatechol,3),glutinosalactone A(4),金圣草黄素(chrysoeriol,5),芹菜素(apigenin,6),木犀草素(luteolin,7),其中化合物1为新化合物. |
| 关 键 词： | 地黄 地上部分 化学成分 苯甲醛类 |
| 收稿时间： | 2014/12/29 0:00:00 |
A new benzaldehyde from aerial part of Rehmannia glutinosa |
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| ZOU Yan,ZHANG Lei,XU Jie-kun,CHENG Qian,YE Xian-sheng,LI Ping,ZHANG Wei-ku and LI Yong-ji.A new benzaldehyde from aerial part of Rehmannia glutinosa[J].China Journal of Chinese Materia Medica,2015,40(7):1316-1319. | |
| Authors: | ZOU Yan ZHANG Lei XU Jie-kun CHENG Qian YE Xian-sheng LI Ping ZHANG Wei-ku and LI Yong-ji |
| Institution: | Department of Pharmacology, Institute of Clinical Medical Sciences, China-Japan Friendship Hospital, Beijing 100029, China;School of Pharmacy, Heilongjiang University of Chinese Medicine, Harbin 150040, China,Department of Pharmacology, Institute of Clinical Medical Sciences, China-Japan Friendship Hospital, Beijing 100029, China,School of Basic Medical Sciences, Beijing University of Chinese Medicine, Beijing 100029, China,School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 100029, China,School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 100029, China,Department of Pharmacology, Institute of Clinical Medical Sciences, China-Japan Friendship Hospital, Beijing 100029, China,Department of Pharmacology, Institute of Clinical Medical Sciences, China-Japan Friendship Hospital, Beijing 100029, China and School of Pharmacy, Heilongjiang University of Chinese Medicine, Harbin 150040, China |
| Abstract: | A new benzaldehyde, 3-hydroxy-4-(4-(2-hydroxyethyl)phenoxy) benzaldehyde(1), together with six known compounds, including isovanillic acid(2), pyrocatechol(3), glutinosalactone A(4), chrysoeriol(5), apigenin(6) and luteolin(7) were isolated from aerial part of Rehmannia glutinosa.The compounds were isolated by macroporous resin, silica gel, Sephadex LH-20 and HPLC chromatographies.The chemical structures of 1-7 were elucidated on the basis of spectral analysis(MS, 1D NMR and 2D NMR). |
| Keywords: | Rehmannia glutinosa aerial part chemical constituents benzaldehyde |