A new lignan from <Emphasis Type="Italic">Aphanamixis polystachya</Emphasis> |
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| Authors: | Samir?Kumar?Sadhu Panadda?Phattanawasin M?Shahabuddin?Kabin?Choudhuri Takashi?Ohtsuki Email author" target="_blank">Masami?IshibashiEmail author |
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| Institution: | (1) Graduate School of Pharmaceutical Sciences, Chiba University, 1-33 Yayoi-cho, Inage-ku, Chiba 263-8522, Japan;(2) Pharmacy Discipline, Life Science School, Khulna University, Khulna 9208, Bangladesh;(3) Faculty of Pharmacy, Silpakorn University, Nakorn Pathom, 73000, Thailand;(4) Department of Pharmacy, Faculty of Biological Science, Jahangirnagar University, Savar, Dhaka, Bangladesh |
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| Abstract: | A new lignan, polystachyol (1), two lignan glycosides, lyoniside (2) and nudiposide (3), and a sterol, ergosta-4,6,8(14),22-tetraen-3-one (4), with stigmasterol, and oleic and linoleic acids, have been isolated from an MeOH extract of the dried bark of Aphanamixis polystachya. The structures of the isolated compounds were elucidated by analysis of 1D and 2D NMR and mass spectroscopic data. The compounds did not have growth inhibitory activity against HeLa cells. |
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| Keywords: | Aphanamixis polystachya Meliaceae Polystachyol Lignan Sterol Cell growth inhibitory activity |
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