|
|||||
|
|
| 制备中药复方当归补血微丸的2种方法比较 | |
| 引用本文： | 陈红霞,贾晓斌 范晨怡 施亚芳 魏惠华.制备中药复方当归补血微丸的2种方法比较[J].中国中药杂志,2008,33(24):2905-2908. |
| 作者姓名： | 陈红霞 贾晓斌 范晨怡 施亚芳 魏惠华 |
| 作者单位： | 1. 江苏大学药学院,江苏,镇江,212013;江苏省中医药研究院中药新型给药系统重点实验室国家中医药管理局名医名方适宜剂型重点研究室,江苏,南京,210028 2. 江苏省中医药研究院中药新型给药系统重点实验室国家中医药管理局名医名方适宜剂型重点研究室,江苏,南京,210028 |
| 基金项目： | 江苏省135工程重点人才项目，国家中医药局科学技术专项基金 |
| 摘 要： | 目的：比较挤出滚圆法和流化床包衣法制备中药微丸的特点。方法：对挤出滚圆法和流化床包衣法制备微丸的原理、制备流程进行比较，并对2种方法所制备的当归补血微丸进行粉体学、收率和体外溶出等考察。结果：用挤出滚圆法制备的当归补血微丸圆整度好，大小均匀，收率高，体外溶出快。结论：2种方法均能制备当归补血微丸，但挤出滚圆法优于流化床包衣法。 |
| 关 键 词： | 挤出滚圆法 流化床包衣法 微丸 当归补血方 粉体学性质 体外溶出度 |
| 收稿时间： | 1/1/1900 12:00:00 AM |
| 修稿时间： | 1/1/1900 12:00:00 AM |
Comparison of two kinds of methods to prepare Chinese medicine Danggui Buxue formula pellets |
|
| CHEN Hong-xia; JIA Xiao-bin; FAN Chen-yi; SHI Ya-fang; WEI Hui-hua.Comparison of two kinds of methods to prepare Chinese medicine Danggui Buxue formula pellets[J].China Journal of Chinese Materia Medica,2008,33(24):2905-2908. |
|
| Authors: | CHEN Hong-xia; JIA Xiao-bin; FAN Chen-yi; SHI Ya-fang; WEI Hui-hua |
| Abstract: | The pellet-preparating theories and processes of two kinds of methods of extrusion-spheronization and fluid-bed coating method were compared. The micromeritic properties, yield and in vitro dissolution of Danggui Buxue pellets prepared by the two methods were determined. Results showed that the Danggui Buxue pellets prepared by extrusion-spheronization were all spheral with smooth surface, the yield of those pellets was higher and in vitro dissolution of those pellets was more satisfactory. So the two kinds of methods were all suitable to prepare Dang-gui-bu-xue pellets, but Extrusion-spheronization was superior to fluid-bed coating method. |
| Keywords: | extrusion-spheronization fluid-bed coating method pellets Dangui Buxue formula micromeritic properties in vitro dissolution |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |