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Polychlorinated dibenzo‐p‐dioxins and dibenzofurans levels in piglet liver with various diseases
Authors:Jeoung Hwa Shin  Won Hyun Ji  Chanhee Chae  Shela Gorinstein  Yun Gyong Ahn
Affiliation:1. Seoul Center, Korea Basic Science Institute, Seoul, South Korea;2. Institute of Mine Reclamation Technology, Mine Reclamation Corporation, Wonju, South Korea;3. College of Veterinary Medicine, Seoul National University, Seoul, South Korea;4. Institute for Drug Research, School of Pharmacy, Hadassah Medical School, The Hebrew University, Jerusalem, Israel;5. Western Seoul Center, Korea Basic Science Institute, Seoul, South Korea
Abstract:This study deals with the levels of toxic polychlorinated dibenzo‐p‐dioxin and furan congeners (PCDD/Fs) in the livers of piglets affected by infectious diseases using isotope dilution high‐resolution gas chromatography/high‐resolution mass spectrometry (HRGC/HRMS). Seventeen toxic congeners in the liver samples infected with bacterial and viral diseases were compared. For porcine reproductive and respiratory syndrome virus (PRRSV) samples, the North American‐ and European‐type PRRS diseases were observed. This study shows that there are significantly different levels of PCDD/Fs, present, which vary according to the types of diseases as evidenced by our analysis of the piglet liver samples.
Keywords:polychlorinated dibenzo‐p‐dioxins/furans  piglet  bacillus nature diseases  porcine reproductive and respiratory syndrome virus (PRRSV)
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