早期先兆流产患者微量元素含量检测的临床意义

目的 探讨妊娠妇女体内微量元素含量与发生先兆流产的关系.方法 比较98例早期先兆流产孕妇、97例正常早孕期妇女以及101例非孕育龄期健康妇女的临床资料,分析孕早期微量元素铜（cuprum,Cu）、锌（zinc,Zn）、钙（calcium,Ca）、镁（magnesium,Mg）、铁（ferri,Fe）、铅（plumbum,Pb）、镉（cadmium,Cd）七项指标的变化情况及其与先兆流产的关系.结果 三组间一般临床资料比较,差异均无统计学意义（P均＞0.05）.三组间Cu、Zn、Ca、Mg和Fe含量差异均有统计学意义（P均＜0.05）,而Pb和Cd含量差异均无统计学意义（P均＞0.05）.与正常非孕组比较,正常早孕组Cu水平上升,Zn水平下降,早期先兆流产组Zn、Ca、Mg、Fe水平均下降,且差异均有统计学意义（P均＜0.05）;与正常早孕组比较,早期先兆流产组Cu、Ca、Mg水平均下降,且差异均有统计学意义（P均＜0.05）.结论 微量元素Cu、Zn、Ca、Mg、Fe在妊娠早期中起着重要作用,其缺乏可能是引起先兆流产的原因之一.因此在计划怀孕前及早孕期要注意摄取含Cu、Zn、Ca、Mg、Fe丰富的食物,补充体内必须的微量元素,以减少先兆流产的发生.

The clinical significance of trace elements detection in the threatened abortion patients

Objective To investigate the relationship between trace elements content and threatened abortion in pregnant women. Methods Clinical data of 98 early threatened abortion pregnant women, 97 normal early pregnant women and 101 normal non-pregnant women of child-bearing age were compared. The changes of the seven trace elements, including cuprum （Cu）, zinc （Zn）, calcium （Ca）, magnesium（Mg）, Ferri （Fe）, plumbum （Pb） and cadmium （Cd） in early pregnant women and its relationship with threatened abortion were analyzed. Results There were no statistical significance in the differences of general conditions among three groups （Pall〉0.05）. There were statistical significance in the differences of Cu ,Zn, Ca, Mg and Fe levels among three groups （Pall〈O.05）, but the differences of Pb and Cd levels among three groups all had no statistical significance （Pall〉0.05）. Compared with normal non-pregnant group, the level of Cu raised and Zn reduced in normal early pregnancy group, the levels of Zn, Ca, Mg and Fe in early threatened abortion group were all reduced, and the differences all had statistical significance （Pall〈0.05）. Compared with normal early pregnancy group, the levels of Cu, Ca and Mg in early threatened abortion group were all reduced, and the differences all had statistical significance （Pall〈O.05）. Conclusion Trace elements, including Cu, Zn, Ca, Mg and Fe, play an important role in early pregnancy and their loss may be one of the reasons of early threatened abortion. Therefore, it is necessary for the early pregnancy and the palnning pregnant women to pay attention to absorb aliment which full of Cu, Zn, Ca, Mg, and Fe, in order to reduce the occurrence of threatened abortion.