中西医结合治疗盆腔炎性疾病的临床研究

目的探讨中药二丹红藤败酱汤联合通络灌肠颗粒基础上加用抗生素治疗盆腔炎性疾病（pelvic inflammatory disease,PID）的疗效。方法选择安徽中医药大学第一附属医院妇科78例PID患者,依据症状、体征和病程进行病情严重程度评分,随机分为3组,分别为中西医结合治疗组（A组）、中药治疗组（B组）和西药治疗组（C组）,比较3组患者的治疗效果。结果A组总有效率为96.2%,B组为80.8%,C组为69.2%,A组疗效明显优于B组及C组（P〈0.05）。A组在改善下腹痛、腰骶胀痛、带下增多等症状及子宫活动受限或压痛体征方面,明显优于B组及C组（P〈0.05）。B组在改善下腹痛症状及缓解子宫活动受限或压痛体征方面明显优于C组（P〈0.05）。A组和B组患者在治疗后C反应蛋白均下降明显（P〈0.05）,其中A组的下降幅度最大。结论中药二丹红藤败酱汤联合通络灌肠颗粒配合抗生素对于治疗PID具有一定优势。

Application of integrated Chinese-western therapy for pelvic inflammatory disease

Objective To explore the clinical efficacy of combination of Erdan Hongteng Baijiang decoction and dredging collaterals en- ema granules with antibiotics for pelvic inflammatory disease （PID）. Methods Totally 78 cases of pelvic inflammatory disease were selected and graded according to the severity of the disease. All patients were randomized into 3 groups ： group A was treated by integrat- ed Chinese-western therapy, group B by traditional Chinese medicine only and group C by antibiotics only. The results of treatment were compared among 3 groups. Results The total effective rate was 96.2% in group A, which was better than group B （80.8%） and group C （69.2%） （ P 〈 0.05 ）. Group A was also better in amelioration of hypogastralgia, lumbosacral pain, morbid leucorrhea, motion limitation or tenderness of uterus than group B and group C （ P 〈 0.05 ）. Group B was better in amelioration of hypogastralgia and motion limitation or tenderness of uterus than group C （ P 〈 0.05）. The level of C-reaction protein decreased significantly after therapy in both group A and group B （ P 〈 0.05 ）, while the decreasing range in group A was higher than in group B （ P 〈 0.05 ）. Conclusions Appli- cation of integrated Chinese-western therapy has advantages in the treatment of pelvic inflammatory disease.