Evaluation of delta-aminolaevulinic acid excretion in random urine samples of children |
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Authors: | A Hudák G Kiss M Náray E Süveges |
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Institution: | (1) Department of Analytical and Clinical Chemistry, National Institute of Occupational Health, P.O. Box 22, H-1450 Budapest, Hungary |
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Abstract: | Urinary delta-aminolaevulinic acid ( -ALA) excretion was evaluated in random urine samples of 191 healthy children, aged 2–14 years, with blood lead levels <0.8 mol/l (mean ± SD: 0.34±0.13), erythrocyte zinc-protoporphyrin <70 mol/mol haem (mean ± SD: 50.4±8.0) and blood haemoglobin >6.8 mmol/l (mean ± SD: 8.2±0.5). It was found that uncorrected -ALA concentration and -ALA/creatinine ratio are age-dependent, whereas the ratio of -ALA/logarithm of creatinine concentration (mean ± SD: 55.3±13.5 mol/log mmol) is independent of age and sex. The authors recommend the use of this parameter for the assessment of -ALA excretion in random urine samples in children |
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Keywords: | Urinary delta-aminolaevulinic acid Normal value in children |
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