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Evaluation of delta-aminolaevulinic acid excretion in random urine samples of children
Authors:A Hudák  G Kiss  M Náray  E Süveges
Institution:(1) Department of Analytical and Clinical Chemistry, National Institute of Occupational Health, P.O. Box 22, H-1450 Budapest, Hungary
Abstract:Urinary delta-aminolaevulinic acid (delta-ALA) excretion was evaluated in random urine samples of 191 healthy children, aged 2–14 years, with blood lead levels <0.8 mgrmol/l (mean ± SD: 0.34±0.13), erythrocyte zinc-protoporphyrin <70 mgrmol/mol haem (mean ± SD: 50.4±8.0) and blood haemoglobin >6.8 mmol/l (mean ± SD: 8.2±0.5). It was found that uncorrected delta-ALA concentration and delta-ALA/creatinine ratio are age-dependent, whereas the ratio of delta-ALA/logarithm of creatinine concentration (mean ± SD: 55.3±13.5 mgrmol/log mmol) is independent of age and sex. The authors recommend the use of this parameter for the assessment of delta-ALA excretion in random urine samples in children
Keywords:Urinary  delta-aminolaevulinic acid  Normal value in children
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