| 钙拮抗剂维拉帕米抑制牙龈成纤维细胞从组织块中的移动 |
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| 引用本文： | 栾庆先,曹采方.钙拮抗剂维拉帕米抑制牙龈成纤维细胞从组织块中的移动[J].现代口腔医学杂志,2003,17(3):212-214. |
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| 作者姓名： | 栾庆先 曹采方 |
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| 作者单位： | 100081,北京大学口腔医学院牙周科 |
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| 摘 要： | 目的 评价维拉帕米对牙龈成纤维细胞移出的影响。方法 采用牙龈组织块培养的方法，在培养液中加入10^-4M维拉帕米，观察牙龈成纤维细胞的移出。结果 在维拉帕米的作用下，组织决周围无细胞移出。撤除维拉帕米后，组织块周围出现成纤维细胞。结论 维拉帕米抑制牙龈成纤维细胞的迁移。
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| 关 键 词： | 钙拮抗剂 维拉帕米 成纤维细胞 牙龈组织块 培养 细胞迁移 |
| 修稿时间： | 2002年6月24日 |
The inhibition of verapamil on gingival fibroblast migration from tissue fragment |
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| LUAN Qingxian,CAO Caifang.The inhibition of verapamil on gingival fibroblast migration from tissue fragment[J].Journal of Modern Stomatology,2003,17(3):212-214. |
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| Authors: | LUAN Qingxian CAO Caifang |
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| Institution: | LUAN Qingxian,CAO Caifang. Department of Periodontology,Peking University School of Stomatology 100081 |
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| Abstract: | Objective To evaluate the influence of verapamil on gingival fibroblast migration. Methods Cell migration from gingival fragment cultured in medium containing 10-4M verapamil was observed. Results There was no cell migration from tissue fragment cultured with medium containing 10 M verapamil. After withdrawal of verapamil, fibroblast was able to migrate from the gingival fragment. Conclusion Verapamil inhibits migration of gingival fibroblasts. |
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| Keywords: | Verapamil Cell migration Gingival fibroblast |
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