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127例药物不良反应分析
引用本文:苏万增,王青,王敏茹,王新梅,张咏梅.127例药物不良反应分析[J].药物不良反应杂志,2003,5(1):8-11.
作者姓名:苏万增  王青  王敏茹  王新梅  张咏梅
作者单位:青岛铁路医院,山东,266002
摘    要:目的:分析引起不良反应的药物临床表现及防治。方法:回顾性分析临床用药发生不良反应的情况。结果:127例不良反应中,心血管药物77例,占60.63%;其它为内分泌、激素药物22例,占17.32%;抗生素11例,占8.66%;抗癌药3例,占2.36%;其它14例,占11.02%。重症不良反应48例,占37.79%;死亡6例,占4.72%.结论:心血管药物可能引致较严重的不良反应。

关 键 词:药物不良反应  心血管药物

Analysis of adverse reactions in 127 cases
Su Wanzeng,Wang Qing,Wang Minru,Wang Xinmei,Zhang Yongmei.Analysis of adverse reactions in 127 cases[J].Adverse Drug Reactions Journal,2003,5(1):8-11.
Authors:Su Wanzeng  Wang Qing  Wang Minru  Wang Xinmei  Zhang Yongmei
Abstract:Objective: To analyse the clinical manifestations and management of drug-induced adverse reactions. Method: The inpatients of 1989-2001 were retrospected, who developed unwanted reactions during treatment courses. Results.- In 127 cases of adverse reactions cardiovascular drug-induced ones accounted for 77 cases (60.63%),followed by hormones (22 cases, 17.32%), antibiotics ( leases, 8.66%), antineoplastic drugs (3 cases, 2.36%) and others (Meases, 11.02%). Among them were 48 cases of severe reactions (37.79%), resulting in 6 deaths (4.72%) . Serious reactions included anaphylaxis, laryngeal edema, ventricular tachycardia, angioneurotic edema and acute renal failure. Conclusion: Adverse reactions can be associated with many drugs, mostly with cardiovascular drugs.
Keywords:adverse drug reactions  cardiovascular drugs
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