| 人工组织神经移植物桥接狗坐骨神经缺损后的机体免疫功能反应 |
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| 引用本文： | 苏丽,钱繷虎,王晓冬,张沛云,汪晓莺,刘晓娟. 人工组织神经移植物桥接狗坐骨神经缺损后的机体免疫功能反应[J]. 南通医学院学报, 2002, 22(1): 33-34 |
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| 作者姓名： | 苏丽 钱繷虎 王晓冬 张沛云 汪晓莺 刘晓娟 |
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| 作者单位： | 1. 南通医学院微生物学教研室,南通,226001
2. 南通医学院神经科学研究所 |
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| 基金项目： | 国家自然科学基金资助 ( 30 0 70 2 5 5 )，江苏省自然科学基金资助 ( BJ2 0 0 0 32 2 ) |
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| 摘 要： | 目的：观察机体免疫系统对人工组织神经移植物的反应。方法：将人工组织神经移植物桥接到狗的坐骨神经缺损处，并在术前和术后6个月时分别取血，进行淋巴细胞转化试验、E花环试验，同时光镜观察术后6个月时再生神经中白细胞浸润的情况。结果：人工组织神经移植物植入后未见排斥反应产生。结论：人工组织神经移植具有较好的生物相容性。
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| 关 键 词： | 人工组织神经移植物 淋巴细胞转化 E花环 移植排斥 狗 坐骨神经缺损 免疫功能反应 |
| 文章编号： | 1000-2057(2002)01-0033-02 |
| 修稿时间： | 2001-05-28 |
IMMUNE RESPONSE TO ARTIFICIAL NERVE GRAFT BRIDGED DOG''''S SCIATIC NERVE GAP |
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| SU Li,QIAN Jihu,WANG Xiaodong,et al. IMMUNE RESPONSE TO ARTIFICIAL NERVE GRAFT BRIDGED DOG''''S SCIATIC NERVE GAP[J]. ACTA Academiae Medicinae Nantong, 2002, 22(1): 33-34 |
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| Authors: | SU Li QIAN Jihu WANG Xiaodong et al |
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| Affiliation: | SU Li,QIAN Jihu,1WANG Xiaodong,et al |
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| Abstract: | Objective: To observe immune system's response to artificial nerve graft.Methods: Artificial nerve graft was bridged sciatic nerve gap. Immune function of the dogs was evaluated by lymphocyte transformation test and erythrocyte rosette test before operation and 6 months after operation . The situation of leucocyte infiltrate was observed under microscope 6 months after operation .Results: Graft rejection was not observed after artificial nerve graft had been transplanted. Conclusions: There was better biocompatibility between artificial nerve graft and organism. |
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| Keywords: | A rtificial nerve graft Lymphocyte transformation Erythrocyte rosette Graft rejection Dog |
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