芬太尼透皮贴剂在肝癌介入治疗后疼痛的疗效观察

目的 观察芬太尼透皮贴剂治疗肝癌介入治疗后疼痛的临床疗效及不良反应。方法 将321例肝癌介入后疼痛患者，随机分为芬太尼透皮贴剂组和对照组（给予口服奥施康定片治疗）。治疗前后分别观察临床疗效、不良反应等。结果 临床疗效的改善两组之间总有效率差异无显著性（P〉0．05），但不良反应差异有显著性（P〈0．05）。结论 芬太尼透皮贴剂用于治疗肝癌介入治疗后疼痛，疗效确切，安全可靠，不良反应小。

Study on the curative effect of transdermal fentanyl in pain treatment after interventional therapy for liver cancer

Objective To evaluate the efficacy of transdermal fentanyl in pain treatment after interventional therapy for liver cancer.Methods 321 liver cancer cases who got pain after interventional therapy were divided into two groups,the treatment group included 123 cases with transdermal fentanly and the control one included 198 cases with OxyContin taking orally.The curative effect and incidences of adverse effect,etc were observed.Rusults The difference of curative effect ratio between two groups is not significant(P>0.05).but there is distinguished difference between them about incidents of adverse effects respectively(P<0.05).Conclusion Transdermal fentanyl in pain treatment after interventional therapy for liver cancer has reliable efficacy,safety and less incident of adverse effects.