胃癌根治术后早期肠内营养支持的应用研究

目的 探讨胃癌根治术后早期肠内营养的可行性、安全性和临床效果。方法 将42例胃癌病人于术后第1d随机分为肠内营养（EN组，n-24）和普通输液（对照组，n-18）2组，并分别在营养支持前后各测定1次体重、肝肾功能、血糖、电解质、血清蛋白、血红蛋白、免疫球蛋白，临床观察生命体征、胃肠道功能恢复情况及各种不良反应。结果 2组病例在观察期间均无死亡、无严重并发症、肝肾功能均无明显变化。EN组血清蛋白、前白蛋白和转铁蛋白水平在营养支持后明显升高（P〈0．01），体重下降减慢。同时，EN组肛门恢复排气时间较对照组显著缩短。结论 胃肠道手术后早期肠内营养支持安全、可行，在改善机体营养状态方面有显著作用，并可促进和维护胃肠道功能，且费用较低。

Study of Early Enterai Nutrition in Post-operative Patients with Stomach Cancer

Objective To explore the feasibility and safety of early post-operative enteral nutrition (EN) for patients with stomach cancer. The effects of EN were compared with those of routine supplement. Methods 42 cases of stomach cancer were randomly divided into EN group (n=24) and control group (n=18) without any nutritional support. Parameters including the body weight, the renal and liver functions, blood glucose, electrolytes, plasma protein, hemoglobin, immunog globulin and lymphocyte count were measured before and after nutritionl support. The complications,vital signs and resumption of gastrointestinal function were carefully observed. Results No mortality and serious morbidity occurred in both two groups, nether was there any evidence of impaired renal and liver function . The levels of serum albumin, prealbumin and transferrin were significantly elevated after nutritional support in the EN groap (P<0.01), while the decline in body weight attenuated as compared with the control group. The bowel movement resumed significantly earlier in the EN group than in the control group. Conclusions Early EN for Post-operative patients with stomach cancer is Safe and feasible. EN is superior in terms of resumption of gastrointestinal function. It is more cost-effective.