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自制房间隔缺损封堵器疗效和安全性研究
引用本文:周达新,葛均波,张国辉,潘翠珍,张峰,沈成兴,程蕾蕾. 自制房间隔缺损封堵器疗效和安全性研究[J]. 中国临床医学, 2002, 9(6): 630-631
作者姓名:周达新  葛均波  张国辉  潘翠珍  张峰  沈成兴  程蕾蕾
作者单位:上海市心血管病研究所,复旦大学附属中山医院心内科,上海,200032
摘    要:目的:应用我院和上海形状记忆金属研究所研制房间隔缺损(ASD)封堵器治疗房间隔缺损研究其疗效和安全性。方法:38例ASD患者,男性12例,女性26,年龄15~64岁(43.36±17.79岁),ASD在5~43mm,肺动脉压力在35.83±8.13mmHg,使用自制的7~42mm的封堵器,经股静脉穿刺,在体表超声心动图或食管超声心动图的指引下进行房间隔缺损的封堵。术前1d开始服用肠溶阿斯匹林200mg/d(儿童按5mg/kg服用),术后1个月改为100mg/d(儿童按3mg/kg服用),持续服用肠溶阿司匹林治疗6个月。术后1个月、3个月、6个月门诊随访X线胸片和体表超声心动图。结果:28例手术全部成功,手术成功率为100%,术中无任何严重的并发症,即刻检查超声心动图,3~8个月的超声心动图随访检查,均无房水平的分流、无栓塞性疾病等并发症,术后当天1例发现有心包积液,经急症外科手术发现为左心耳处渗血,手术中行食管超声心动图检查,证实房间隔封堵器位置合适无残余分流。结论:我们研制的房间隔缺损封堵器安全、有效。

关 键 词:安全性 房间隔缺损 自制房间隔缺损封堵器 疗效 ASD 病例分析

Appraisal of Efficacy and Safety of Inventive Atrial Septal Occluder Device
Zhou Daxin Ge Junbo Zhang Guohui,et al.. Appraisal of Efficacy and Safety of Inventive Atrial Septal Occluder Device[J]. Chinese Journal Of Clinical Medicine, 2002, 9(6): 630-631
Authors:Zhou Daxin Ge Junbo Zhang Guohui  et al.
Abstract:Objective: To evaluate efficacy and safety of inventive atrial-septal defect occluder device. Methods: 28 patients with secundum ASD, aged 15-64 years old , 13 male, 15 female, were studied. And the diameter of ASD was between 5mm and 43mm. The pulmonary pressure was 35.83
Keywords:Atrial septal defect Inventive atrial-septal defect occluder device Efficacy
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