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A new chromosome translocation (3;21) in M2 acute lymphocytic leukemia |
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| Authors: | A Caimo C M Parodi S De Filippi C Rabitti R Cerri M Risso A Bacigalupo A Castellaneta A Marmont |
| Abstract: | High-resolution chromosome banding studies were carried out on leukemic cells from a young patient with acute nonlymphocytic leukemia (ANLL), M2 of the FAB classification. A new chromosomal abnormality involving a translocation between chromosomes 3 and 21 was observed, i.e., t(3;21)(p14;q22). A complete remission was never obtained in spite of aggressive chemotherapy and the patient died 8 months after diagnosis. |
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