温经活血方足浴治疗糖尿病下肢周围神经病变的疗效观察

目的　观察温经活血方足浴治疗糖尿病下肢周围神经病变的疗效。方法　筛选同济大学附属东方医院胶州医院2019年4月至2021年10月收治的172例糖尿病下肢周围神经病变患者作为研究对象，随机分为对照组与治疗组，每组86例。其中对照组：男44例，女42例，年龄36～76岁，采用常规治疗+温水足浴。治疗组：男46例，女40例，年龄38～78岁，在常规治疗的基础上加用温经活血方足浴，于治疗前后行症状评分评估、神经传导速度检测、生化指标，比较两组患者的临床疗效。计量资料以均数±标准差（x±s）表示，采用t检验，计数资料用率（％）表示，采用χ²检验。结果　比较两组空腹血糖（FBG）、血糖（PBG）、糖化血红蛋白（HbA1c）、低密度脂蛋白胆固醇（LDL-C）等生化指标，对照组分别为（7.56+1.23）mmol/L、（9.86±0.89）mmol/L、（7.13±0.56）%、（3.05±0.57）mmol/L，治疗组分别为（6.62+0.58）mmol/L、（7.97±1.02）mmol/L、（6.27±1.11）%、（1.78±0.63）mmol/L，差异均有统计学意义（均P<0.05）。治疗组神经传导速度总有效率为89.5%（77/86），明显优于对照组［69.8%（60/86）］，差异有统计学意义（χ²=10.366，P<0.05）。对照组多伦多临床评分系统（TCSS）、中医证候积分评分分别为（10.21±1.23）分、（2.21±0.18）分；治疗组分别为（8.15±1.28）分、（1.01±0.38）分。两组上述指标比较差异均有统计学意义（t=10.761、26.466，均P<0.05）。结论　温经活血方足浴治疗糖尿病下肢周围神经病变的临床疗效、改善神经传导速度及降低生化指标等方面效果理想，利于患者病情恢复。

Foot bath with Wenjing Huoxue Fang for diabetic peripheral neuropathy on lower limbs

Objective　To observe the efficacy of foot bath with Wenjing Huoxue Fang in the treatment of diabetic peripheral neuropathy on lower limbs. Methods　From April 2019 to October 2021, 172 patients with diabetic peripheral neuropathy on lower limbs treated at Jiaozhou Branch, Shanghai East Hospital, Tongji University were selected as the research objects, and were randomly divided into a control group and a treatment group, with 86 cases in each group. The control group had 44 males and 42 females who were 36-76 years old, and took conventional treatment and warm water foot bath. The treatment group had 46 males and 40 females who were 38-78 years old; on the basis of conventional treatment, they took foot bath with Wenjing Huoxue Fang. The symptom scores, nerve conduction velocities, and biochemical indicators before and after treatment and the clinical efficacies were compared between the two groups. The measurement data were expressed as (x±s), and compared by t test. The enumeration data were expressed as cases (%), and compared by χ² test. Results　The levels of fasting blood glucose (FBG), postprandial glucose (PBG), glycosylated hemoglobin (HbA1c), and low density lipoprotein cholesterol (LDL-C) were (7.56+1.23) mmol/L, (9.86±0.89) mmol/L, (7.13±0.56)%, and (3.05±0.57) mmol/L in the control group, and were (6.62+0.58) mmol/L, (7.97±1.02) mmol/L, (6.27±1.11)%, and (1.78±0.63) mmol/L in the treatment group, with statistical differences (all P<0.05). The total effective rate of nerve conduction velocity was 89.5% (77/86) in the treatment group, and was 69.8% (60/86) in the control group, with a statistical difference (χ²=10.366, P<0.05). The scores of traditional Chinese medicine syndrome and Toronto Scoring System were (10.21±1.23) and (2.21±0.18) in the control group, and were (8.15±1.28) and (1.01±0.38) in the treatment group, with statistical differences (t=10.761 and 26.466, both P<0.05). Conclusion　Foot bath with Wenjing Huoxue Fang for diabetic peripheral neuropathy on lower limbs has ideal clinical efficacy, can improve the patients' nerve conduction velocity and biochemical indicator levels, and is conducive to the patients' recovery.