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| 空气粉尘污染对大脑影响的MRI研究进展 | |
| 引用本文： | 祝玉琦,尹波,于泽宽,耿道颖.空气粉尘污染对大脑影响的MRI研究进展[J].国际医学放射学杂志,2022,45(4):427-430. |
| 作者姓名： | 祝玉琦 尹波 于泽宽 耿道颖 |
| 作者单位： | 1 复旦大学上海医学院,上海 200032 2 复旦大学附属华山医院放射科 3 复旦大学附属华山北院放射科 4 复旦大学工程与应用技术研究院 |
| 基金项目： | 国家自然科学基金(82103964);上海市科学技术委员会“科技创新行动计划”临床医学领域重点专项(19411951200) |
| 摘 要： | 空气粉尘污染会对大脑结构与功能产生损害。MRI技术可用于观察空气粉尘污染对脑结构与功能的影响，包括基于T1加权的三维磁化强度预备快速梯度回波（T1WI-3D-MPRAGE）、液体衰减反转恢复（FLAIR）、扩散加权成像（DWI）、扩散张量成像（DTI）、血氧水平依赖成像（BOLD）和MR波谱成像（MRS）等序列。MRI不仅能观察到空气粉尘对大脑整体形态、灰白质以及脑深部核团等重要解剖结构的影响，还能反映大脑神经纤维发育、脑网络功能连接和神经元代谢方面的功能改变。就MRI用于空气粉尘污染对大脑影响的研究及进展作一综述。 |
| 关 键 词： | 空气污染 颗粒污染物 磁共振成像 结构成像 功能成像 脑 |
| 收稿时间： | 2021-10-09 |
Progress of magnetic resonance imaging research on the effects of air particulate matter pollution on brain |
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| ZHU Yuqi,YIN Bo,YU Zekuan,GENG Daoying.Progress of magnetic resonance imaging research on the effects of air particulate matter pollution on brain[J].International Journal of Medical Radiology,2022,45(4):427-430. | |
| Authors: | ZHU Yuqi YIN Bo YU Zekuan GENG Daoying |
| Institution: | 1 Shanghai Medical College of Fudan University, Shanghai 200032, China 2 Department of Radiology, Huashan Hospital, Fudan University 3 Department of Radiology, Huashan Hospital North, Fudan University 4 Academy for Engineering and Technology, Fudan University |
| Abstract: | Particulate matter (PM) pollution can damage the structure and function of brain. A variety of MRI techniques can be used to observe the effects of PM pollution on brain structure and function, including T1WI-3D-magnetization prepared rapid acquisition gradient echo sequences (T1WI-3D-MPRAGE), fluid-attenuated inversion recovery (FLAIR), diffusion weighted imaging (DWI), diffusion tensor imaging (DTI), blood oxygen level dependent imaging (BOLD), MR spectroscopy (MRS) and so on. MRI can not only be used to observe the effects of PM on important anatomical structures such as the overall morphology of the brain, gray and white matter, and deep brain nuclei, but also evaluate functional changes in brain nerve fiber development, functional connectivity of brain networks, and neuronal metabolism. This article reviews the progress of MRI research on the effects of PM pollution on brain. |
| Keywords: | Air pollution Particulate matter Magnetic resonance imaging Structural imaging Functional imaging Brain |
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