儿童胃肠道间质瘤致重度贫血2例

儿童胃肠道间质瘤是一种罕见的胃肠道实体肿瘤，早期往往表现为贫血，因其临床表现无明显特异性，容易误诊。肿瘤原发病灶多见于胃壁或小肠肠壁，如果瘤体体积较小，也容易漏诊。腹部B超、CT及胃肠镜是确诊该病的主要方法。该病的治疗除了手术治疗以外，还应根据基因检测及病理免疫组化结果给予必要的靶向药物治疗。本文报道2021年至今西安市儿童医院收治的2例以贫血为主诉，住院后诊断为胃肠道间质瘤的患儿。现结合相关文献对其诊治过程进行分析。

Two cases of severe anemia caused by gastrointestinal stromal tumor in children

Gastrointestinal stromal tumor in children is a rare solid tumor of gastrointestinal tract. As the clinical manifestations are not specific, it often shows anemia in the early stage and is easy to be misdiagnosed. The primary focus is located in the wall of the stomach or small intestine, and if the tumor size is small, it is easy to be miss diagnosed. Abdominal color ultrasound, CT, and gastroenteroscopy are the main methods to diagnose the disease. In addition to surgical treatment, necessary targeted drugs should be given according to the results of gene detection and pathological immunohistochemistry. This paper reported two cases of gastrointestinal stromal tumor admitted to Xi 'an Children's Hospital since 2021 with the chief complaint of anemia. The processes of diagnosis and treatment were analyzed based on relevant literatures.