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Comparison of the Effects of Intraradicular Materials on the Incidence of Fatal Root Fracture in Immature Teeth Treated with Mineral Trioxide Aggregate Apexification: A Retrospective Study
Institution:1. Department of Operative Dentistry and Endodontics, Faculty of Dentistry, Mahidol University, Bangkok, Thailand;2. Department of Community Dentistry, Faculty of Dentistry, Mahidol University, Bangkok, Thailand;3. Dental Center, Bangkok Hospital, Bangkok, Thailand;1. The State Key Laboratory Breeding Base of Basic Science of Stomatology (Hubei-MOST) and Key Laboratory of Oral Biomedicine Ministry of Education, School and Hospital of Stomatology, Wuhan University, Wuhan, China;2. Department of Endodontics, The Dental College of Georgia, Augusta University, Augusta, Georgia;1. Department of Dental Services, King Abdulaziz Medical City, Ministry of National Guard Health Affairs, Jeddah, Saudi Arabia;2. Department of Endodontics, School of Dental Medicine, University of Pennsylvania, Philadelphia, Pennsylvania;1. Key Laboratory of Shaanxi Province for Craniofacial Precision Medicine Research, College of Stomatology, Xi''an Jiaotong University, Xi''an, Shaanxi, China;2. Clinical Research Center of Shaanxi Province for Dental and Maxillofacial Diseases, College of Stomatology, Xi''an Jiaotong University, Xi''an, Shaanxi, China;3. State Key Laboratory of Military Stomatology and National Clinical Research Center for Oral Diseases and Shaanxi Key Laboratory of Stomatology, Department of Prosthodontics, School of Stomatology, The Fourth Military Medical University, Xi''an, China;1. Department of Endodontics, Division of Clinical Sciences, Faculty of Dentistry, Okan University, Istanbul, Turkey;2. Department of Conservative Dentistry, School of Dentistry, Dental Research Institute, Pusan National University, Yangsan, Korea;3. Department of Conservative Dentistry, School of Dentistry, The University of Jordan, Amman, Jordan;4. Department of Conservative Dentistry, School of Dentistry, Kyungpook National University, Daegu, Korea;1. Unit of Endodontology, Division of Restorative Dental Science, University College London Eastman Dental Institute, London, United Kingdom;2. Division of Biomaterials and Tissue Engineering, University College London Eastman Dental Institute, London, United Kingdom;3. The Discoveries Centre for Regenerative and Precision Medicine, University College London, London, United Kingdom;4. Department of Nanobiomedical Science and BK21 Plus NBM, Global Research Center for Regenerative Medicine, Dankook University, Cheonan, Republic of Korea;6. University College London Eastman-Korea Dental Medicine Innovation Centre, Dankook University, Cheonan, Republic of Korea;1. Division of Clinical Dentistry, School of Dentistry, International Medical University, Kuala Lumpur, Malaysia;3. School of Pharmacy, International Medical University, Kuala Lumpur, Malaysia;4. School of Postgraduate Studies, International Medical University, Kuala Lumpur, Malaysia;2. Department of Restorative Dentistry, Faculty of Dentistry, University of Malaya, Kuala Lumpur, Malaysia;6. Department of Endodontics, School of Dental Medicine, University of Pennsylvania, Philadelphia, Pennsylvania
Abstract:IntroductionThis study aimed to compare the incidence of root fractures that led to extraction in immature teeth endodontically treated by mineral trioxide aggregate (MTA) apexification and were restored with either reinforced (resin composite or fiber post) or nonreinforced (gutta percha or MTA) intraradicular materials.MethodsNecrotic immature teeth treated with MTA apexification from 1996 to 2017 were selected according to the inclusion and exclusion criteria. Intraradicular materials and preoperative and treatment factors were obtained from dental charts and radiographs. The incidence of fatal root facture was identified. Kaplan-Meier survival analysis and the Cox proportional hazard model were used to show the survival rate and predisposing factors at a significance level of .05.ResultsThe average recall period was 30 months. The incidence of root fracture in the teeth restored with the reinforced materials was 5.5%, which was not significantly different from the nonreinforced materials (8.3%). Furthermore, the fracture rates between the fiber post and resin composite groups were not significantly different. Two significant predisposing factors influencing the incidence of root fracture were detected: preoperative external inflammatory root resorption (hazard ratio = 26.86; P < .05) and patient age > 15 years (hazard ratio = 8.60, P < .05).ConclusionsImmature teeth treated with MTA apexification and restored with the reinforced or nonreinforced intraradicular materials exhibited a similar rate of root fracture. Preoperative external inflammatory root resorption and patient age > 15 years were found to be the predisposing factors that significantly increased the incidence of root fracture.
Keywords:Immature tooth  intraradicular material  mineral trioxide aggregate apexification  root fracture  survival rate
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