eZIS在脑血流灌注SPECT诊断神经退行性痴呆中的临床应用

简易Z评分成像系统（eZIS）是一种基于统计参数图和三维立体定向表面投影的辅助脑血流灌注SPECT图像自动诊断的统计分析方法，可以用于痴呆、帕金森病、共济失调和运动神经元病等神经系统疾病的诊断。与其他计算机辅助分析方法相比，eZIS可提供正常数据库，并通过图像转换程序实现不同机构的数据共享，使未来多中心、大样本量的临床研究成为可能。笔者就eZIS在脑血流灌注SPECT诊断神经退行性痴呆中的临床应用进行综述，旨在提高临床医师对eZIS的认识，促进其在临床及科研工作中的应用。

Clinical application of eZIS in the diagnosis of neurodegenerative dementia by cerebral blood perfusion SPECT

The easy Z-score imaging system (eZIS) is a statistical analysis method based on statistical parametric mapping and three-dimensional stereotactic surface projection to assist the automatic diagnosis of cerebral blood perfusion SPECT imaging, which can be used in the diagnosis of nervous system diseases such as dementia, Parkinson disease, ataxia and motor neuron disease. Compared with other computer-aided analysis methods, eZIS can provide a normal database, and realize data sharing among different institutions through image conversion program, so that the future multi-center, large sample clinical research is possible. In this review, the clinical application of eZIS in the diagnosis of neurodegenerative dementia by cerebral blood perfusion SPECT is reviewed in order to improve clinicians' understanding of eZIS and promote its application in clinical and scientific research work.