| 结直肠癌患者肠道菌群与肠道免疫微环境关系的研究进展 |
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| 引用本文： | 朱琨 卢清军 任翔 蒋宏. 结直肠癌患者肠道菌群与肠道免疫微环境关系的研究进展[J]. 国际医药卫生导报, 2022, 28(24): 3419. DOI: 10.3760/cma.j.issn.1007-1245.2022.24.002 |
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| 作者姓名： | 朱琨 卢清军 任翔 蒋宏 |
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| 作者单位： | 滨州医学院附属医院结直肠疝外科，滨州 256000 |
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| 基金项目： | 国家卫生健康委科技发展中心“微创手术临床应用规范研究”课题（WA2021RW12）；滨州医学院“临床+X”项目基金（BY2021LCX21）；滨州医学院科研计划与科研启动基金（BY2019KYQD42，BY2019KJ11） |
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| 摘 要： | 结直肠癌（colorectal cancer，CRC）是常见的消化道恶性肿瘤之一，其发生、发展与饮食、遗传及免疫等多种因素关系密切。目前，大量的基础及临床研究开始聚焦肠道菌群在CRC免疫调控中的作用。本文通过对CRC患者肠道菌群构成、肠道菌群与免疫微环境的关系等作一综述，重点分析CRC患者肠道菌群对肠道免疫微环境的调控，为CRC的预防及治疗提供新的研究思路。
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| 关 键 词： | 结直肠癌 肠道菌群 肠道免疫微环境 |
| 收稿时间： | 2022-08-24 |
Progress in the relationship between intestinal flora and intestinalimmune microenvironment in colorectal cancer patients |
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| Zhu Kun,Lu Qingjun,Ren Xiang,Jiang Hong. Progress in the relationship between intestinal flora and intestinalimmune microenvironment in colorectal cancer patients[J]. International Medicine & Health Guidance News, 2022, 28(24): 3419. DOI: 10.3760/cma.j.issn.1007-1245.2022.24.002 |
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| Authors: | Zhu Kun Lu Qingjun Ren Xiang Jiang Hong |
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| Affiliation: | Departments of Colorectal Hernia Surgery, Binzhou Medical UniversityHospital, Binzhou 256000, China |
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| Abstract: | Colorectal cancer (CRC) is one of the mostcommonly malignant tumors of digestive tract. Its occurrence and developmentare affected by many factors such as diet, genetics, and immunity. At present,more studies have turned to the role of intestinal flora in immune regulationof CRC. In this review, the composition of intestinal flora and therelationship between intestinal flora and intestinal immune microenvironment inCRC patients are studied, and we emphatically discuss the regulation ofintestinal flora in intestinal immune microenvironment in CRC patients in orderto provide a new way for the prevention and treatment of CRC. |
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| Keywords: | Colorectal cancer Intestinal flora Intestinal immune microenvironment |
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