1岁以下婴儿ICare手持回弹式眼压计眼压正常值及RetCam检查对其影响的研究

 目的 分析1岁以下婴儿正常眼压值及眼底广域数字成像系统（RetCam3）视网膜筛查对眼压的影响。设计 前瞻性病例系列。研究对象 2019~2020年于广东省妇幼保健院行筛查的≤1岁婴儿285例（570眼），其中男性176例。选择同期在我院门诊就诊且眼压正常的成年人102例（204眼）作为对照。方法 使用ICare手持回弹式眼压计测量婴儿RetCam3筛查前后的眼压值，比较筛查前后眼压变化及其与成年人的异同。主要指标 眼压。结果 婴儿双眼平均眼压（13.04±3.04） mmHg，左、右眼眼压差异无统计学意义（t=-1.68，P=0.10）。成年人双眼平均眼压（16.82±2.36）mmHg，婴儿眼压较成年人低（t=-18.14，P＜0.01）。不同性别婴儿的眼压比较无统计学意义（t=0.20，P=0.85）。行RetCam3眼底检查后眼压（13.93±3.20） mmHg较检查前眼压（12.88±3.12） mmHg升高（t=5.09，P＜0.01），出生时胎龄＜32周组眼底检查前后眼压的差值（1.64±3.76）mmHg高于≥32周组（0.75±3.22）mmHg （t=2.12，P=0.04）。结论 1岁以下婴儿平均眼压较成年人低；RetCam3眼底检查可引起婴儿眼压轻微升高，且对出生胎龄小的婴儿影响更明显。（眼科， 2022， 31： 345-348）

Study on the normal intraocular pressure in infants under 1 year old by ICare hand-held rebound tonometer and the effect of retinal examination with RetCam on it

Objective To observ the normal intraocular pressure (IOP) of infants under 1 year old and to analyze the effect of retinal examination with wide field digital fundus imaging system (RetCam3) on their IOP. Design Prospective case series. Participants 285 cases (570 eyes) of ≤1 year old infants born at 24~40 weeks of pregnancy, wherein 176 were males, and 102 adult cases (204 eyes) with normal IOP, in Guangdong Women and Children Hospital between 2019 to 2020. Methods IOPs before and after RetCam3 retinal examinations in infacts as well as adults were measured by the ICare hand-held rebound tonometer. The differences of IOP between before and after RetCam3 retinal examinations and between infacts and adults were compared. Main Outcome Measures IOPs. Results The mean IOP of both eyes of infants was (13.04±3.04) mmHg, there was no significant difference between left and right IOP (t=-1.68，P=0.10). The both eyes mean IOP of adults was (16.82±2.36) mmHg. The IOP of infants was lower than that of adults (t=-18.14，P＜0.01). There was no statistical difference of IOP between different genders for infants (t=0.20，P=0.85). The IOP after RetCam3 examination was (13.93±3.20) mmHg, which was higher than that before examination (12.88±3.12 mmHg) (t=5.09，P＜0.01). The difference of IOP before and after fundus examination was more higher in <32 weeks group (1.64±3.76 mmHg) than ≥32 weeks group (0.75±3.22 mmHg) (t=2.12，P=0.04).  Conclusion The mean IOP of infants ≤1 year old is lower than adults. RetCam3 retinal examinationcan cause mild IOP increase in infants, and the effect is more obvious in the infants with smaller gestational age. (Ophthalmol CHN, 2022, 31: 345-348)