全数字钼靶提高同时性双侧乳腺癌检出率的临床研究

目的 评价全数字钼靶在临床上检测同时性双侧原发乳腺癌的准确率，探讨其在同时性双侧原发乳腺癌的临床诊断和治疗中的价值。方法 选取本院2006年6月～2011年12月间收治的12例同时性双侧原发乳腺癌患者，所有病例均行全数字钼靶X线摄影、彩色多普勒超声和MRI检查，并与术后病理结果对比分析；术后进行为期2年的随访。结果 总检出灵敏度：全数字钼靶诊断的灵敏度为83.3%，超声和MRI检查的灵敏度分别为54.2%、45.8%，与全数字钼靶比较差异均具有统计学意义（P<0.01,P<0.05）；第一原发癌的检出灵敏度：全数字钼靶为83.3%，超声和MRI检查分别为66.7%、50.0%，与全数字钼靶相比差异均无统计学意义（P>0.05）；第二原发癌的检出灵敏度：全数字钼靶诊断的灵敏度为83.3%，超声和MRI检查的灵敏度均41.7%，与全数字钼靶相比，差异均具有统计学意义（P<0.05）。术后随访的结果表明，未发现漏诊的对侧乳腺癌患者。结论 全数字钼靶对双侧原发癌中较早期的一侧及第二原发癌的检出率均高于超声及MRI检查，能够更早更准确地发现病灶。

The clinical research of all-digital mammography improve the detection rate of simultaneity of bilateral breast cancer

Objective To evaluate the accuracy rate of using full digital mammography to detect the simultaneous bilateral primary breast cancer, and to explore its value in the diagnosis and treatment of bilateral primary breast cancer for the same period. Methods Twelve cases of bilateral primary breast cancer for the same period were selected in our hospital between 2008-2011, and all the patients were underwent digital mammography X-ray photography, and color Doppler ultrasound, MRI, and all of them were comparative with pathological results analysis; postoperative follow-up period of two years, and the survival curves was made. Results The total detection accuracy： the all-digital mammography was 83.3%, ultrasound and MRI accuracy were 54.2% and 45.8% respectively. Compared to the all-digital mammography, the differences were statistically significant （P<0.05, P<0.01）. First primary cancer detection accuracy： the all-digital mammography was 83.3%, ultrasound and MRI accuracy were 66.7% and 50.0% respectively. Compared to the all-digital mammography, there has no significant difference （P>0.05）. Detection accuracy of second primary cancers： the all-digital mammography was 100%, both of ultrasound and MRI were 41.7%. Compared to the all-digital mammography, the differences were statistically significant （P<0.05）. The postoperative follow-up results show that contralateral breast cancer patients found no missed diagnosis. Conclusion The detection rate of all-digital mammography was higher than ultrasound and MRI for bilateral primary cancer early on one side and a second primary cancer, and it can be more accurate and earlier to found the lesions by using the all-digital mammography.