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Structural Properties of the Lipid A Component of the Lipopolysaccharide(Endotoxin)Isolated from Bacteriodes fragilis NCTC 9343
引用本文:焦炳华,何炬斌,余伟明,周炳荣,丁锡竞. Structural Properties of the Lipid A Component of the Lipopolysaccharide(Endotoxin)Isolated from Bacteriodes fragilis NCTC 9343[J]. 中国人民解放军军医大学学报, 1989, 0(4)
作者姓名:焦炳华  何炬斌  余伟明  周炳荣  丁锡竞
作者单位:Endotoxin Division Department of Microbiology,Second Military Medical University,Shanghai 200433,Endotoxin Division,Department of Microbiology,Second Military Medical University,Shanghai 200433,Endotoxin Division,Department of Microbiology,Second Military Medical University,Shanghai 200433,Endotoxin Division,Department of Microbiology,Second Military Medical University,Shanghai 200433,Endotoxin Division,Department of Microbiology,Second Military Medical University,Shanghai 200433
摘    要:Various chemical and gas-liquid chromatographic analyses indicate that the lipid A,backbone of the lipopolysaccharide(LPS)isolated from B.fragilis NCTC 9343 is chemically con-stitutεd by a β1,6-interlinked D-glucosamine disaccharide.It is phosphorylated at its 1-positionby a glvcosidic-linkage while the ester-linked phosphate at 4'—position present generally in otherlipid A is depleted.The lipid A is lower fatty acylated in the amount of 5.2 fatty acids/lipid Amolecule(of which 0.73 forms 3-acyloxyacyl groups).The LPS containing such an incompletelipid A component has been shown endowina with a weaker endotoxicitv.


Structural Properties of the Lipid A Component of the Lipopolysaccharide(Endotoxin)Isolated from Bacteriodes fragilis NCTC 9343
Jiao Binghua,He Jubin,Yu Weiming,Zhou Bingrong,DingShijin Endotoxin Division. Structural Properties of the Lipid A Component of the Lipopolysaccharide(Endotoxin)Isolated from Bacteriodes fragilis NCTC 9343[J]. Journal of Medical Colleges of PLA(China), 1989, 0(4)
Authors:Jiao Binghua  He Jubin  Yu Weiming  Zhou Bingrong  DingShijin Endotoxin Division
Affiliation:Jiao Binghua,He Jubin,Yu Weiming,Zhou Bingrong,DingShijin Endotoxin Division,Department of Microbiology,Second Military Medical University,Shanghai 20043
Abstract:
Keywords:B.fragills  lipopolysaccharide(endotoxin)  lipid A  gas-liquid chromatography  structural properties
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