Supratentorial primitive neuroectodermal tumours: diffusion-weighted MRI |
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| Authors: | J. Klisch H. Husstedt S. Hennings V. v. Velthoven A. Pagenstecher M. Schumacher |
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| Affiliation: | (1) Department of Neuroradiology, University of Freiburg, Breisacher Strasse 64, 79106 Freiburg, Germany e-mail: Klisch@nz 11.ukl.uni-freiburg.de, Tel.: + 49-7 61-2 70 51 80, Fax: + 49-7 61-2 70 51 95, DE;(2) Department of Neurosurgery, University of Freiburg, Freiburg, Germany, DE;(3) Department of Neuropathology, University of Freiburg, Freiburg, Germany, DE |
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| Abstract: | We report the clinical and pathological findings of supratentorial primitive neuroectodermal tumours (PNETs). These are rare, poorly differentiated, highly malignant neoplasms occurring primarily in young individuals. They frequently show dissemination to the spinal cord and sometimes also beyond neuraxis. Preoperative radiological diagnosis is difficult, due to the nonspecific CT and MRI characteristics. Our findings indicate that diffusion-weighted imaging (DWI) can be used to show the solid portion of the tumour preoperatively and to monitor postsurgical recovery. We describe the MRI findings in three patients with histologically confirmed supratentorial PNET, focussing on the role of DWI for improving the specificity of radiological diagnosis. Received: 27 January 1999/Accepted: 3 September 1999 |
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| Keywords: | Primitive neuroectodermal tumours Brain, neoplasms Magnetic resonance imaging, diffusion weighted |
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