| 利妥昔单抗治疗非霍奇金淋巴瘤9例 |
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| 引用本文： | 于晓宁,陈学良. 利妥昔单抗治疗非霍奇金淋巴瘤9例[J]. 肿瘤学杂志, 2005, 11(1): 58-59 |
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| 作者姓名： | 于晓宁 陈学良 |
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| 作者单位： | 山东大学齐鲁医院,山东,济南,250012 |
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| 摘 要： | [目的]观察利妥昔单抗治疗非霍奇金淋巴瘤的疗效和毒性反应.[方法]9例均为住院患者,用药剂量为375mg/m2,每周1次,连续4～6次,可与化疗方案联用.[结果]CR5例,PR1例,SD1例,PD2例,总有效率(RR)为66.67%,其中Ⅰ A期6例,ⅢB期1例,ⅣB期2例.主要毒副反应为发热、寒战、胸闷、一过性皮疹及短暂的肝功能指标升高等.[结论]利妥昔单抗联合化疗是治疗低度恶性非霍奇金淋巴瘤有效而安全的方案.
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| 关 键 词： | 淋巴瘤,非霍奇金 免疫疗法 利妥昔单抗 单克隆抗体 |
| 文章编号： | 1671-170X(2005)01-0058-02 |
| 修稿时间： | 2004-08-22 |
Effect of Rituximab on Non-Hodgkin Lymphoma: A Report of 9 Cases |
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| YU Xiao-ning,CHEN Xue-liang. Effect of Rituximab on Non-Hodgkin Lymphoma: A Report of 9 Cases[J]. Journal of Chinese Oncology, 2005, 11(1): 58-59 |
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| Authors: | YU Xiao-ning CHEN Xue-liang |
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| Abstract: | To investigate the response and toxicity of rituximab in the treatment for Non-Hodgkin lymphoma. Nine cases of inpatient received rituximab 375mg/m2 once a week, four to six times combined with chemotherapy (8 cases). Five cases were complete remission and one showed partial remission. The overall response rate was 66.67%. The major toxicities were fever, chill, tire, tetter, transitory abnormal liver function and so on. [Conclusion] Rituximab is effective for patients with low-malignant non-Hodgkin lymphomas. |
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| Keywords: | CD20 |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
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