| 铅和噪声联合作用对作业工人血SOD、MDA含量的影响 |
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| 引用本文： | 李南春,陈瑞梅,陈朝军,黄江洁. 铅和噪声联合作用对作业工人血SOD、MDA含量的影响[J]. 国际医药卫生导报, 2014, 20(4): 465-467 |
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| 作者姓名： | 李南春 陈瑞梅 陈朝军 黄江洁 |
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| 作者单位： | 李南春 (511515,清远市疾病预防控制中心)； 陈瑞梅 (511515,清远市疾病预防控制中心)； 陈朝军 (511515,清远市疾病预防控制中心)； 黄江洁 (511515,清远市疾病预防控制中心)； |
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| 基金项目： | 清远市科技计划项目(项目编号：00092681320615009) |
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| 摘 要： | 目的 探讨铅和噪声联合作用对工人的血清超氧化物歧化酶（SOD）、丙二醛（MDA）含量的影响.方法 选择年龄、工龄及接触噪声强度相近的A（铅和噪声联合作用组）、B（单纯噪声组）两组工人,测定血SOD、MDA含量,同时测定血铅含量,并比较两组数据差异.结果 A、B两组工人血SOD值分别为（65.2±16.3） U/ml、（63.8±13.9） U/ml,两组工人血SOD值无明显差异（P＞0.05）；A、B两组工人血MDA含量分别为（6.81±3.12）nmol/ml、（5.02±2.36）nmol/ml,两组工人血MDA含量差异有统计学意义（P＜0.05）.结论 铅和噪声联合作用可加重机体自由基损害和脂质过氧化.
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| 关 键 词： | 铅 噪声 联合作用 SOD MDA |
The combined effects of lead and noise exposure on serum SOD and MDA levels |
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| Li Nanchun,Chen Ruimei,Chen Chaojun,Huang Jiangjie. The combined effects of lead and noise exposure on serum SOD and MDA levels[J]. International Medicine & Health Guidance News, 2014, 20(4): 465-467 |
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| Authors: | Li Nanchun Chen Ruimei Chen Chaojun Huang Jiangjie |
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| Affiliation: | 1.Centers for Disease Control and Prevention of Qingyuan City, Qingyuan 511515, China;) |
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| Abstract: | Objective To explore the combined effects of lead and noise exposure on serum SOD and MDA levels.Methods Workers in group A （lead and noise exposure） and group B （noise exposure） had matched age,length of working and intensity of noise.The serum SOD and MDA levels were detected and compared between two groups.Results The serum SOD levels of group A and group B were （65.2 ± 16.3）U/ml,（63.8 ± 13.9）U/ml respectively,without significant difference between two groups （P ＞ 0.05）.The serum MDA levels of group A and group B were （6.81 ± 3.12） nmol/ml,（5.02 ± 2.36） nmol/ml respectively,with significant difference between two groups （P ＜ 0.05）.Conclusion Lead combined with noise exposure may worsen free radical impairment and lipid peroxidation. |
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| Keywords: | Lead Noise Combined effects SOD MDA |
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