Diagnostik und Therapie der akuten myeloischen Leukämie des Erwachsenen

In recent years knowledge about the biology of acute myeloid leukemia has improved tremendously. This has led to the necessity of using complex diagnostic procedures and introducing new classification systems. In parallel possibilities evolved for risk-adapted or specific therapeutic strategies within subgroups of the disease. New prognostic factors and therapeutic options led to significant confusion regarding the day-to-day routine in AML therapy. The report presented here gives an overview of modern diagnostic procedures, new prognostic factors, and up-to-date prognostic classification systems in AML. Furthermore, established therapeutic strategies are described and discussed in the context of the most recent literature. Finally, new therapeutic possibilities and their perspectives for the future are highlighted.