| 刺激新生期注射谷氨酸单钠大鼠下丘脑弓状核对丘脑束旁核单位痛放电的影响 |
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| 引用本文： | 陈向阳,殷伟平,印其章. 刺激新生期注射谷氨酸单钠大鼠下丘脑弓状核对丘脑束旁核单位痛放电的影响[J]. 苏州大学学报(自然科学版), 1986, 0(4) |
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| 作者姓名： | 陈向阳 殷伟平 印其章 |
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| 作者单位： | 苏州医学院电生理研究室，苏州医学院电生理研究室，苏州医学院电生理研究室 |
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| 摘 要： | 本实验在新生期注射谷氨酸单钠的成年大鼠上观察刺激下丘脑弓状(ARC)对丘脑束旁核(PF)单位痛放电的影响。结果:①电刺激大鼠ARC对PF单位痛诱发放电有明显的抑制作用。②新生期住射谷氨酸单钠,选择性地破坏大鼠ARC区神经元后,刺激ARC对PF单位痛放电的抑制作用比正常动物明显减少(P<0.01)。实验结果提示:刺激ARC的抑制效应可能是通过兴奋ARC区神经元而实现的。
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| 关 键 词： | 弓状核 束旁核 谷氨酸单钠 痛诱发放电 |
The Effect of Hypothalamic Arcuate Stimulation on the Pain-evoked Unit Discharges of Thalamic Parafascicular Nucleus in MSG-treated Rats |
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| Chen Xiangyang. The Effect of Hypothalamic Arcuate Stimulation on the Pain-evoked Unit Discharges of Thalamic Parafascicular Nucleus in MSG-treated Rats[J]. Suzhou University Journal of Medical Science, 1986, 0(4) |
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| Authors: | Chen Xiangyang |
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| Affiliation: | Chen Xiangyang |
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| Abstract: | (1) Electical stimulation of hypothalamic arcuate nucleus(ARC)of rats had a marked inhibitory effect on the pain-evoked unit discharges of parafascicular nucleus. (2) The inhibitory effect of ARC stimulation decreased markedly(P< 0. 01)in rats neonatally treated with monosodium glutamate. (3) It is suggested that the inhibitory effect of ARC stimulation is mediated by activating neurons in ARC. |
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| Keywords: | arcuate nucleus parafaseicular nucleus monosodium glutamate pain-evoked discharge |
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