伴中央-颞区棘波的儿童良性癫痫56便临床和脑电图特点研究分析

目的分析伴中央-颞区棘波的儿童良性癫痫（BECCTS）的临床及脑电图（EEG）特点。方法收集2002～2011年本院神经内科收治的56例BECCTS患儿的临床资料并进行回顾性分析。结果56例患儿起病年龄3～14岁，高发年龄为5～10岁。多数患儿同生期无异常事件，精神发育运动正常，神经系统查体及影像检查正常．发作与睡眠密切相关，以部分运动性发作为特征，脑电图特点为发作间期EEG可见患者中央区及颞区出现高幅的尖波放电，以双向尖波为特征。56例应用抗癫痫药物治疗后停止发作，39例已停药，1例复发，16例正减药。结论BECCTS患儿具有特征性临床及脑电图，抗癫痫药物单药治疗反应良好，预后良好。

Clinical and electroencephalogram characteristics of benign epilepsy of childhood with centro-temporal spikes in 56 cases

Objective To analyze the clinical and electroencephalogram （EEG） characteristics of benign epilepsy of childhood with central-temporal spikes （BECCTS）. Methods Clinical data of 56 cases of BECCTS children in our de partment from 2002 to 2011 were selected and retrospectively analyzed. Results The onset age of 56 cases of BECCTS children were 3 to 14 years old, and the high incidence age was 5 to lO years old. There was no abnormality on mental development, physical examinations in nervous system, or imaging examinations at perinatal stages. The occurrence was closely related with sleep characterized by partial motor seizure. The feature of EEG on seizure of epilepsy displayed two-dimensional spike discharge in high amplitude in central-temporal areas. The epileptic seizures were ceased after applying antiepileptic drug in 56 patients, and 39 patients ceased to take medicine, one case recurred and 16 cases were reducing medicine. Conclusion The BECCTS patients are characterized by specific clinical presentation and EEG. Application of single antiepileptic drug can obtain a good effect and favorable prognosis.