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Complexation in the retention of benzoic acids on a bonded xanthine HPLC stationary phase |
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| Authors: | A.J. Repta L.A. Sternson K.A. Mereish N.M. Meltzer |
| Affiliation: | Pharmaceutical Chemistry Department, The University of Kansas, Lawrence, KS 66045 U.S.A. |
| Abstract: | The retention of a number of benzoic acids was determined using a bonded xanthine stationary phase (XSP). Retention of benzoate on XSP was studied as a function of pH and organic modifier composition of the mobile phase. The measured retention for 10 substituted benzoic acids was correlated with the complexation constants previously reported for these compounds with theophylline. |
| Keywords: | Correspondence: A.J. Repta Pharmaceutical Chemistry Department University of Kansas Lawrence KS 66045 U.S.A.. |
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