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痔瘘熏洗凝胶剂药效学初步研究
引用本文:周青,严士海,达庆国,周琴妹,朱萱萱,陈玉根. 痔瘘熏洗凝胶剂药效学初步研究[J]. 西部中医药, 2011, 24(9): 19-21
作者姓名:周青  严士海  达庆国  周琴妹  朱萱萱  陈玉根
作者单位:1. 南京中医药大学第一临床医学院,江苏,南京,210029
2. 江苏省中医院
基金项目:2009-2010年度江苏省中医药局科技项目
摘    要:目的:观察痔瘘熏洗凝胶剂的抗炎、镇痛效果.方法:选取雌性大鼠分组后通过建立角叉菜胶肛周肿胀模型,观察痔瘘熏洗凝胶剂对实验性痔疮的抗炎作用;选取雌性小鼠分组后通过热板法观察痔瘘熏洗凝胶剂的镇痛作用.结果:痔瘘熏洗剂及其改进剂型--痔瘘熏洗凝胶剂对角叉菜胶所致大鼠肛周肿胀均有显著的抑制作用,对热传导引起的疼痛有确切的镇痛作...

关 键 词:痔瘘熏洗凝胶剂  肛周水肿模型  痛阈值  抗炎  镇痛  朱秉宜

Preliminary Study of ZhiLou XunXi Gel on Pharmacodynamics
ZHOU Qing,YAN Shi-hai,DA Qing-guo,ZHOU qin-mei,ZHU Xuan-xuan,CHEN Yu-gen. Preliminary Study of ZhiLou XunXi Gel on Pharmacodynamics[J]. Western Journal of Traditional Chinese Medicine, 2011, 24(9): 19-21
Authors:ZHOU Qing  YAN Shi-hai  DA Qing-guo  ZHOU qin-mei  ZHU Xuan-xuan  CHEN Yu-gen
Affiliation:ZHOU Qing1,YAN Shi-hai2,DA Qing-guo2,ZHOU qin-mei2,ZHU Xuan-xuan2,CHEN Yu-gen2 1 First Clinical Medical College,Nanjing University of TCM,Jiangsu Nanjing China 210029,2 Jiangsu Province Hospital of TCM
Abstract:Objective:To investigate the anti-inflammatory and analgestic effect of ZhiLou XunXi Gel.Method: Perineal swelling induced by carrageenan in rats were used to evaluate the anti-inflammatory on experimental hemorrhoids of ZhiLou XunXi Gel.The analgesic effects of ZhiLou XunXi Gel were tested by observing the rats reaction to the pain stimulated by heat.Result:ZhiLou XunXi Gle and its improved formulations greatly suppressed perineal swelling induced by carrageenan in rats.ZhiLouXunXi Gle could significantly ...
Keywords:ZhiLou XunXi Gel  perineal edema model  pain threshold  anti-inflammatory  analgesic  ZHU Bing-yi  
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