颅脑损伤致继发性癫痫的多因素分析

目的]探讨颅脑损伤后继发性癫痫发生的相关因素。方法]回顾性分析186例颅脑损伤患者的临床资料，在损伤后有癫痫发作和未发作患者间就性剐、年龄、癫痫家族史、损伤部位、损伤类型和损伤程度等暴露因素间差异进行多因素条件logistic回归分析。结果]单因素分析显示癫痫病家族史、损伤类型、损伤程度等暴露因素在癫痫发作和未发作患者之间存在差异，且差异有显著性（P〈O．05）。多因素条件Logistic回归分析显示损伤类型、损伤程度在癫痫发作和未发作患者之间存在差异，且差异有显著性（P〈0．05）。结论]损伤类型、损伤程度为颅脑损伤后继发性癫痫的主要危险因子。

Multiple-factor Analysis of Epilepsy Secondary to Head Injury

Objective] To explore the relative factors of secondary epilepsy after head injury. ｜MethodsJ The clinical data of 186 patients with head injury were analyzed retrospectively. The differences in risk factors such as sex, age, family history of epilepsy, the position, type and degree of the injury between the patients with and without seizure disorder after injury were analyzed by logistic multivariate regression method. Re- sults] Univariate analysis showed that there were significant differences in the risk factors such as family histo- ry of epilepsy, the type and degree of injury between the patients with and without seizure disorder（ P % 0.05）. Multivariate logistic regression analysis showed that there were significant differences in the type and degree of injury between the patients with and without seizure disorder（ P %0.05）. Conclusion] The type and degree of injury are the main independent risk factors of secondary epilepsy after head injury.