| 支气管哮喘患儿治疗前后血清IL-6、IL-10和GM-CSF检测的临床意义 |
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| 引用本文： | 秦文敬.支气管哮喘患儿治疗前后血清IL-6、IL-10和GM-CSF检测的临床意义[J].放射免疫学杂志,2008,21(5):407-408. |
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| 作者姓名： | 秦文敬 |
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| 作者单位： | 江苏省东海县人民医院检验科,222300 |
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| 摘 要： | 目的：探索了支气管哮喘患儿治疗前后血清IL-6、IL-10和GM-CSF水平的变化及临床意义。方法：应用放射免疫分析对33例支气管哮喘患儿进行了治疗前后血清IL-6、IL-10和GM-CSF测定,并与30名正常健康儿作比较。结果：支气管哮喘患儿在治疗前后血清IL-6、IL-10和GM-CSF水平均非常显著地高于正常儿（P〈0.01）,经治疗三个月后则与正常儿组比较无显著性差异（P〉0.05）。结论：检测血清IL-6、IL-10和GM-CSF水平变化对支气管哮喘患儿的治疗、预后均具有重要的临床价值。
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| 关 键 词： | 支气管哮喘 白细胞介素-6 白细胞介素-10 巨噬细胞集落剌激因子 |
Clinical Significance of Determination of Changes of Serum IL-6, IL-10 and GM-CSF Levels After Treatment in Pediatric Patients with Bronchial Asthma |
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| Qin Wenjing.Clinical Significance of Determination of Changes of Serum IL-6, IL-10 and GM-CSF Levels After Treatment in Pediatric Patients with Bronchial Asthma[J].Journal of Radioimmanology,2008,21(5):407-408. |
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| Authors: | Qin Wenjing |
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| Institution: | Qin Wenjing (Department of Clinical Laboratory,Donghai People＇s Hospital,Donghai,Jiangsu 222300) |
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| Abstract: | Objective To explore the changes of Serum IL-6, IL-10 and GM-CSF levels after treatment in pediatric patients with bronchial asthma. Methods Serum IL-6, IL-10 and GM-CSF levels were measured with RIA in 33 pediatric patients with bronchial asthma both before and after treatment as well as in 30 controls. Results Before treatment, the serum IL-6, IL-10 and GM-CSF levels were significantly higher than those in controls (P<0.01). After 3 months treatment, the levels were not significantly different from those ... |
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| Keywords: | bronchial asthma interleukin-6(IL-6) interleukin-10(IL-10) macrophage colony-stimulating factor (M-CSF) |
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