| 功劳去火片的溶出度考察 |
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| 引用本文： | 路玫,黄雪梅,张玲.功劳去火片的溶出度考察[J].中国药房,2001,12(7):424-425. |
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| 作者姓名： | 路玫 黄雪梅 张玲 |
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| 作者单位： | 广西壮族自治区人民医院 |
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| 摘 要： | 目的 :对功劳去火片中的黄芩苷溶出度进行考察 ,为评价和控制药品质量提供依据和参数。方法 :以水为释放介质 ,用高效液相色谱法对功劳去火片的溶出度进行测定和比较。结果 :功劳去火片的T50 为106min～220min ,不同批号样品的溶出参数 (T50、Td、m)有显著性差异 (P<0 01)。结论 :有必要对每批产品进行溶出度检查 ,以保证临床疗效
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| 关 键 词： | 功劳去火片 溶出度 高效液相色谱法 |
| 文章编号： | 1001-0408(2001)07-0424-02 |
| 修稿时间： | 2000年12月6日 |
Study on the Dissolubility of Gonglaoquhuo Tablets |
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| LU Mei,HUANG Xuemei,ZHANG Ling.Study on the Dissolubility of Gonglaoquhuo Tablets[J].China Pharmacy,2001,12(7):424-425. |
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| Authors: | LU Mei HUANG Xuemei ZHANG Ling |
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| Abstract: | OBJECTIVE:The dissolution rates of baicalin in Gonglaoquhuo tablets were determined to provide a basis for evaluating and controlling the drug quality METHODS:The dissolution rates of Gonglaoquhuo tablets with different batch num_bers were determined by HPLC,using water as dissolution medium RESULTS:The T50 of Gonglaoquhuo tablets was 106min～220min and there were significant differences in dissolution parameters(T50,Td,m) between the tablets tested(P<0 01) CON_CLUSION:It is suggested that the dissolubility of each batch of products should be tested to control the quality and ensure clinical efficacy |
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| Keywords: | Gonglaoquhuo tablets dissolubility HPLC |
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