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EANM procedure guideline for 32P phosphate treatment of myeloproliferative diseases
Authors:Jan Tennvall   Boudewijn Brans  Michael Lassmann
Affiliation:(1) Department of Oncology, Lund University Hospital, 221 85 Lund, Sweden;(2) Department of Nuclear Medicine, University Medical Centre, Maastricht, The Netherlands;(3) Clinic for Nuclear Medicine, University Würzburg, Würzburg, Germany
Abstract:Introduction 32P phosphate was the first therapeutic radioisotope, used in leukaemia about 70 years ago. Since then, many new agents for haematological proliferations have been introduced successfully. Today there remains a distinct subgroup of elderly patients with polycythaemia vera and essential thrombocythaemia for whom 32P is the most optimal treatment option, an assertion supported by two large studies with long follow-up. Purpose The purpose of this guideline is to assist the nuclear medicine physician in treating and managing patients who may be candidates for 32P phosphate therapy. An erratum to this article can be found at
Keywords:Guidelines  Nuclear medicine   32P phosphate  Polycythaemia vera  Essential thrombocythaemia  Radionuclide therapy
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