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Graves病眼球突出患者TRAb的检测
引用本文:孙斌,李重文,王彦清,李宝兰,宋补昌. Graves病眼球突出患者TRAb的检测[J]. 山西医科大学学报, 2004, 35(6): 623-625
作者姓名:孙斌  李重文  王彦清  李宝兰  宋补昌
作者单位:山西医科大学第三临床医学院眼科,太原,030053
摘    要:目的 探讨TRAb在Graves病患者并发眼球突出中的作用。方法 对 91例Graves病并发眼球突出患者TRAb检测值与 4 9例未发生眼球突出患者TRAb检测值及两组患者TRAb阳性率进行比较。结果 Graves病并发眼球突出组TRAb活性明显高于不发生眼球突出组 ;并发眼球突出组TRAb阳性检出率显著高于不发生眼球突出组TRAb阳性检出率。结论 TRAb在Graves病患者并发眼球突出过程中起着非常重要的作用。

关 键 词:格雷夫斯病  突眼  抗体  促甲状腺素受体
文章编号:1007-6611(2004)06-0623-03
修稿时间:2004-08-26

Detection of serum TRAb in exophtalmos patients with Graves'''' disease
SUN Bin,LI Chong-wen,WANG Yan-qing,et al. Detection of serum TRAb in exophtalmos patients with Graves'''' disease[J]. Journal of Shanxi Medical University, 2004, 35(6): 623-625
Authors:SUN Bin  LI Chong-wen  WANG Yan-qing  et al
Abstract:Objective To investigate the effect of serum thyrotropin receptor antibodies (TRAb) in exophthalmos patients with Graves'disease. Methods Sera TRAb levels were measured in 91 exophthalmos patients with Graves'disease and 49 no-exophthalmos patients by radio-receptor assay. Results TRAb levels in exohthalmos patients were significantly higher compared with no-exophthalmos patients. Positive rate of TRAb in exophthalmos patients was significantly higher than that in no-exophtalmos patients. Conclusion Serum TRAb levels may play a critical role in the development of exophthalmos patients with Graves'disease.
Keywords:Graves' disease  exophthalmos  antibodies  thyrotropin receptor
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