Panton-Valentine leukocidin genes and staphylococcal chromosomal cassette <Emphasis Type="Italic">mec</Emphasis> types amongst Finnish community-acquired methicillin-resistant <Emphasis Type="Italic">Staphylococcus aureus</Emphasis> strains, 1997–1999 |
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| Authors: | M Kardén-Lilja S Ibrahem J Vuopio-Varkila S Salmenlinna O Lyytikäinen L Siira A Virolainen |
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| Institution: | (1) Department of Bacterial and Inflammatory Diseases, National Public Health Institute, Mannerheimintie 166, 00300 Helsinki, Finland;(2) Haartman Institute, Department of Bacteriology and Immunology, University of Helsinki, P.O. Box 21, 00014 Helsinki, Finland;(3) Department of Infectious Disease Epidemiology, National Public Health Institute, Mannerheimintie 166, 00300 Helsinki, Finland |
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| Abstract: | Methicillin-resistant Staphylococcus aureus (MRSA) strains from Finland covering years 1997–1999 were studied for the presence of Panton-Valentine leukocidin (PVL) gene
loci, and the clinically well-defined community-acquired MRSA (CA-MRSA) strains (n = 108) also for staphylococcal chromosomal cassette mec (SCCmec) and multilocus sequence types (MLST). Only a minority (12%) of the CA-MRSA strains contained the PVL gene loci and possessed
genotypes formerly described as typical to CA-MRSA strains. The majority of these strains were heterogenous by MLST and pulsed-field
gel electrophoresis (PFGE) analysis but, however, harboured the SCCmec cassette type IV. In conclusion, it seems doubtful to consider only molecular characteristics such as the presence of PVL
genes as definite markers for CA-MRSA strains.
This data was partly presented at the 14th European Congress of Clinical Microbiology and Infectious Diseases (ECCMID), May
1–4, 2004, Prague, Czech Republic, Poster no. P1014. |
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