| 用PCR技术同时检测牙菌斑、唾液及胃粘膜中的幽门螺杆菌 |
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| 引用本文： | 徐丽辉,顾虹艳,张小红,王毓明. 用PCR技术同时检测牙菌斑、唾液及胃粘膜中的幽门螺杆菌[J]. 实用口腔医学杂志, 2001, 17(2): 144-146 |
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| 作者姓名： | 徐丽辉 顾虹艳 张小红 王毓明 |
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| 作者单位： | 1. 江苏吴县市第一人民医院口腔科
2. 苏州市第三人民医院 |
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| 摘 要： | 目的：通过同时测定牙菌斑、唾液及胃粘膜中幽门螺杆菌（Hp）以了解口腔中Hp的状态及其与胃粘膜病变的关系。方法：采用PCR技术同时测定牙菌斑、唾液及胃粘膜中的幽门螺杆菌。结果：47例胃粘膜Hp阳性的胃窦炎患者中17例（36．2％）牙菌斑中检出Hp；31例（65．9％）唾液标本Hp阳性。而13例胃粘膜Hp阴性者中仍有2例牙菌斑中检出的Hp，1例呼液中检出Hp。胃粘膜Hp阳性和阴性者之间牙菌斑及唾液Hp检出率的差异有显著性（P＜0．01）。结论：口腔中的Hp可能与胃粘膜中的Hp存在着一定的病因学联系。
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| 关 键 词： | 牙菌斑 唾液 胃粘膜 幽门螺杆菌 聚合酶链反应 |
| 文章编号： | 1001-3733(2001)-02-0144-03 |
| 修稿时间： | 2000-10-16 |
Detection of Helicobacter pylori in dental plaque,saliva and gastric mucosa from the patients with gastritis |
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| Abstract: | Objective:To investigate the etiological relation between oral Helicobacter pylori(Hp) and gastric Hp.Methods:Hp in dental plaque,saliva and gastric mucosa from the patients with gastritis was detected with PCR.Results:Hp was found in dental plaque in 17 cases and in saliva in 31 cases out of 47 patients with gastric Hp positive gastritis respectively.Hp was positive in dental plaque in 2 cases and in saliva in 1 case out of 13 gastritis patients with negative gastric Hp.There was a significant difference of Hp positive rate of dental plaque or saliva between patients with positive gastric Hp and those with negative gastric Hp (P<0.01).Conclusion:Oral Hp may be rellated to gastric Hp. |
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| Keywords: | Dental plaque Saliva Stomach Mucous membrane Helicobacter pylori |
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