布地奈德联用孟鲁司特钠治疗小儿咳嗽变异性哮喘的临床研究

目的探讨布地奈德联用孟鲁司特钠治疗小儿咳嗽变异性哮喘的临床效果。方法选取2017年11月至2019年2月于本院就诊的小儿咳嗽变异性哮喘患儿65例,按随机数表法分为对照组(n=32)和观察组(n=33)。对照组给予布地奈德治疗,观察组给予布地奈德联用孟鲁司特钠治疗,比较两组肺功能及临床症状积分。结果治疗后,观察组患儿PEF、FEV1、FVC、FEV1/FVC均高于对照组,症状积分低于对照组,差异有统计学意义(P<0.05)。结论布地奈德联用孟鲁司特钠治疗小儿咳嗽变异性哮喘可有效改善患者肺功能及临床症状,具有较高的临床应用价值。

Clinical study on budesonide combined with montelukast sodium in treatment of children with cough variant asthma

Objective To investigate the clinical effect of budesonide combined with montelukast sodium in treatment of children with cough variant asthma.Methods 65 children with cough variant asthma who admitted in the hospital from November 2017 to February 2019 were divided into control group(n=32)and observation group(n=33)by random number table.Control group was given budesonide,and observation group was treated with budesonide combined with montelukast sodium.The pulmonary function and clinical symptoms were compared between two groups.Results After treatment,the PEF,FEV1,FVC and FEV1/FVC in observation group were higher than those in control group,and the symptom score of observation group was lower than that of control group(P<0.05).Conclusion Budesonide combined with montelukast sodium in treatment of children with cough variant asthma can improve pulmonary function and clinical symptoms,which has higher clinical application value.