观察恶性肿瘤合并医院感染患者死亡原因与应用抗菌药物的关系

目的 观察恶性肿瘤合并医院感染患者应用抗菌药物与死亡原因的关系.方法 随机选取2018年7至2019年6月本院恶性肿瘤合并医院感染患者190例,采用回顾性分析方法,逐项查阅死亡患者病历,选取条件相符的病历进行登记.结果 190例恶性肿瘤合并医院感染患者中,感染部位主要为下呼吸道、泌尿生殖道,分别占比33.7％、20.0...

Observation of relationship between the cause of death of patients with malignant tumor and nosocomial infection and the use of antibiotics

Objective To observe the relationship between the use of antibiotics and the cause of death of patients with malignant tumor and nosocomial infection.Methods 190 cases of patients with malignant tumor and nosocomial infection in our hospital from July 2018 to June 2019 were randomly selected.By retrospective analysis,the medical records of the dead patients were checked item by item,and the medical records matching the conditions were selected for registration.Results In 190 cases of patients with malignant tumor and nosocomial infection,the main infection sites were lower respiratory tract and urogenital tract,accounting for 33.7%and 20.0%,followed by abdominal cavity,incision and oral mucosa,accounting for 12.1%,10.5%and 10.0%,and finally digestive tract,chest cavity and blood,accounting for 5.8%,4.7%and 3.2%.Two and three combinations of antibiotics were mainly used,accounting for 50.5%and 42.1%,followed by one antibiotic,accounting for 5.8%,and finally four combinations of antibiotics,accounting for 1.6%.2 cases died,the mortality rate was 1.1%(2/190).In terms of Department distribution,there were 92 cases in oncology department,38 cases in urology department,35 cases in general surgery department,11 cases in digestive department,and 14 cases in infectious department;73 cases were surgical system,117 cases were internal system,accounting for 38.4%,61.6%respectively.The mortality rate of patients with internal medicine system 0.9%(5/117)was significantly lower than patients with surgery system 1.4%(1/73)(P<0.05).In terms of the distribution of hospitalization time,103 cases were less than 1 month,87 cases were more than 1 month,accounting for 54.2%and 45.8%,respectively.The difference of mortality between patients with hospital stay≥1 month and patients with hospital stay<1 month[1.1%(5/87),1.0%(1/103)]was not significant.Conclusion The use of antibiotics of patients with malignant tumor and nosocomial infection is closely related to the cause of death.