近、远端胃癌的临床病理生理特点的分析

目的探讨近端胃癌和远端胃癌患者临床病理、生理特点的差异。方法回顾性分析2018年6月至2019年6月在莆田学院附属医院手术成功的102例胃癌患者的临床资料。查阅患者病历资料,记录患者的性别、年龄、体重指数(BMI)、肿瘤大小、淋巴结转移情况、肿瘤分期、并发症情况、术前CEA水平、住院总费用,分析近端胃癌和远端胃癌患者临床病理、生理特点的差异及与预后的关系。结果102例胃癌患者中,近端胃癌65例,远端胃癌37例,近端胃癌发生率(63.7%)高于远端胃癌(36.3%)。近端胃癌组和远端胃癌组男性发病率、BMI、肿瘤大小、淋巴结转移情况、肿瘤分期、并发症、术前CEA水平、住院总费用比较差异无统计学意义;近端胃癌组年龄≥60岁患者占比高于远端胃癌组,差异有统计学意义(P<0.05)。结论莆田地区近端胃癌发病率高于远端胃癌,近端胃癌组年龄≥60岁患者占比高于远端胃癌组。

Clinical pathophysiological characteristics of proximal and distal gastric carcinoma

Objective To investigate the differences of clinicopathological and physiological characteristics between patients with proximal and distal gastric cancer.Methods The clinical data of 102 patients with gastric cancer who underwent successful surgery in The Affiliated Hospital of Putian University from June 2018 to June 2019 were retrospectively analyzed.The patient's medical records were reviewed,including gender,age,body mass index(BMI),tumor size,lymph node metastasis,tumor stage,complications,preoperative CEA level,and total cost of hospitalization,to analyze the differences in clinicopathological and physiological characteristics of patients with proximal and distal gastric cancer and their relationship with prognosis.Results Among the 102 patients with gastric cancer,there were 65 cases of proximal gastric cancer and 37 cases of distal gastric cancer,and the incidence of proximal gastric cancer(63.7%)was higher than that of distal gastric cancer(36.3%).There were no statistically significant differences in male incidence,BMI,tumor size,lymph node metastasis,tumor stage,complications,preoperative CEA level and total hospitalization costs between the proximal and distal gastric cancer groups.The proportion of patients aged≥60 years in the proximal gastric cancer group was higher than that in the distal gastric cancer group,and the difference was statistically significant(P<0.05).Conclusion The incidence of proximal gastric cancer in Putian region was higher than that of distal gastric cancer,and the proportion of patients aged≥60 years in the proximal gastric cancer group was higher than that of the distal gastric cancer group.