改良CKC术对宫颈上皮内瘤变患者病灶残留率及并发症的影响

目的观察宫颈上皮内瘤变患者行改良宫颈冷刀锥切术(CKC)对病灶残留率及并发症的影响。方法选取2017年3月至2019年3月本院收治的80例宫颈上皮内瘤变患者为研究对象,根据随机对照法分为两组,各40例。对照组行宫颈环形电切术(LEEP),观察组行改良CKC治疗。比较两组临床指标、病灶残留率以及术后并发症发生情况。结果观察组手术用时长于对照组,术中出血量多于对照组,差异具有统计学意义(P<0.05);观察组术后切缘阳性率、病灶残留率及术后并发症发生率均低于对照组,但差异无统计学意义。结论两种手术方式治疗宫颈上皮内瘤变均有显著效果,其中LEEP术创伤小,利于患者恢复,而改良CKC术病灶清除率较高,术后并发症较少,临床操作可根据患者病情选择合适手术方式。

Effect of modified CKC operation on residual rate and complications of cervical intraepithelial neoplasia

Objective To observe the effect of modified cervical cold knife conization(CKC)on the residual rate and complications of cervical intraepithelial neoplasia.Methods 80 patients with cervical intraepithelial neoplasia who were admitted to our hospital from March 2017 to March2019 were selected as the research subjects.According to the randomized control method,they were divided into two groups,with 40 cases in each group.The control group received LEEP,and the observation group received modified CKC treatment.The clinical indicators,residual rate of lesions and postoperative complications were compared between the two groups.Results The operation time of the observation group was longer than that of the control group,and the amount of intraoperative blood loss was more than that of the control group,the difference was statistically significant(P<0.05).The positive rate of postoperative resection margins,residual lesion rate and postoperative complications of the observation group were slightly lower than the control group,but the difference was not statistically significant.Conclusion The two surgical methods have significant effects in the treatment of cervical intraepithelial neoplasia.Among them,LEEP is relatively less traumatic and is beneficial to the recovery of patients.Modified CKC has higher rate of lesion clearance and fewer postoperative complications.The clinical operation can choose the appropriate surgical method according to the patient’s condition.