氯诺昔康在妇科腹腔镜术后镇痛中的应用

目的 观察妇科腹腔镜患者术后单次使用氯诺昔康的24h镇痛作用。方法 将妇科腹腔镜择期手术患者90例随机分为A组（氯诺昔康8mg）、B组（氯诺昔康16mg）和c组（对照组），每组30例，A，B组均在术毕注射氯诺昔康．采用视觉模拟法（VAS评分）分别于术后1，4，8，24h作痛觉评分，并记录有无恶心等副作用及术后24h内使用镇痛药物的总次数。结果 使用氯诺昔康的两组患者术后24h内VAS评分显著低于对照组（P〈0．05），B组使用镇痛药的次数明显低于对照组（P〈0．05）。结论妇科腹腔镜术毕单次静脉注射8mg或16mg氯诺昔康可有效缓解术后疼痛，16mg组的镇痛作用更强，且均无明显的不良反应。

Application of Lornoxicam in Postoperative Analgesia of Gynaecological Laparoscopic Operation

Objective To assess the effect of postoperative analgesia with lornoxicam in patients undergoing gynaecological laparoscopic operations.Methods 90 patients scheduled for gynaecological laparoscopic operations were randomly allocated to three groups,group A(lornoxicam 8 mg),group B(lornoxicam 16 mg)and group C(contral group).Lornoxicam was injected before the end of operation in group A and group B.Postoperative pain was assessed by VAS-score at 1,4,8,24 h after end of surgery,side-effects such as nausea and the total number of injecting analgesic were also assessed.Results The patients of the two lornoxicam groups who injected with lornoxicam 8 mg or lornoxicam 16 mg before the end of surgery had significantly lower VAS scores after operation than group C(P < 0.05).Conclusion Lornoxicam 8 mg or lornoxicam 16 mg injected before the end of gynaecological laparoscopic operation provide satifactory postoperative pain relief,the analgesic action of lornoxicam 16 mg is better with no more side-effects.