香菇多糖药理作用的实验研究

将30只小鼠随机分成3组，每组10只，分别用香菇多糖60mg/kg,30mg/kg和生理盐水口服，每日一次。连续8d给药后1h实验发现香菇多糖60mg/kg口服给药能显著提高小鼠的抗疲劳和耐缺氧能力。mg/kg及60mg/kg口服给药均能明显提高小鼠对电信号刺激的反应能力，有助于增强学习记忆力。提示，香菇多糖具有明显的抗衰老，增强体制，促进智能发育的效应。

Experimental Study on the Pharmacological Effect of Lentinan

Thirty mice were divided into 3 groups at random,with each group contaning 10 mice.Oral ad- ministration of Lentinan,extract from Lentinus edodes(Berk)Sing,60 mg/kgand 30 mg/kg was giv- en separately to 2 groups for 8 days,the third group was given normal saline for control.Our study demonstrated that Lentinan of 60 mg/kg orally could increase the capability of fatigue endurance and antianoxia in mice,and that of 30 mg/kg and 60 mg/kg could significantly increase the reactivity of electric signal stimulate.It is suggested that Lentinan may improve the effect of learning and memory. Its mechanism remains to be studied.