云南省某市女性性工作者阴道冲洗与性传播疾病的关系

目的了解云南省某市女性性工作者(FSWs)阴道冲洗情况以及艾滋病病毒(HIV)和各种性传播疾病(STD)的感染情况。方法招募FSWs调查其社会人口统计学、行为学、HIV／AIDS知识以及生殖健康状况,采集静脉血进行HIV、单纯疱疹病毒2型(HSV-2)和梅毒血清学检测,采集尿液、宫颈分泌物和阴道分泌物标本进行尿吗啡、淋球菌和沙眼衣原体及阴道毛滴虫检测。结果共收集血液标本833份,其中84份经确认为HIV抗体阳性,感染率为10．1％,梅毒感染率为8．2％(68／833),HSV-2感染率为68．4％(570／833);阴道和宫颈分泌物标本各832份,淋球菌感染率为11．5％(96／832),沙眼衣原体感染率为28．2％(235／832),阴道毛滴虫感染率为11．9％(99／832)。多因素logistic回归模型分析显示,与阴道冲洗有关的影响因素为汉族、中高档性服务场所、听说过艾滋病、工作场所≥4个、过去一年出现过下腹部疼痛。结论阴道冲洗是HIV和某些STD感染的危险因素。

Study on the association between Vaginal douching and sexually transmitted diseaes among Female sex Workers in a county of Yunnan province

OBJECTIVE: To explore the epidemic characteristics of vaginal douching, human immunodeficiency virus (HIV) and other sexually transmitted diseases(STD) among female sex workers (FSWs) in Yunnan province. METHODS: FSWs were recruited to be investigated on their demographic data, drug abuse and sexual behavior, HIV/AIDS knowledge and procreation health status. Venous blood were collected to test for HIV, herpes simplex virus 2 (HSV-2) and syphilis while urine specimen was for morphine, cervical secretion for Gonorrhoea and Chlamydia trachomatis, and vaginal secretion for Trichomonas. RESULTS: A total number of 833 blood specimen were collected, in which 84 specimen were confirmed to be HIV positive with a prevalence rate of 10.1%. The prevalence rates of syphilis and HSV-2 were 8.2% and 68.4% respectively. 832 vaginal and cervical secretion specimen were collected with the prevalence rates of Gonorrhoea, Chlamydia trachomatis and Trichomonas were 11.5%, 28.2% and 11.9% respectively. In multivariate logistic analysis, the factors associated with vaginal douching were: being Han nationality, locations of sex work at middle/high level, ever heard of HIV/AIDS, emerged hypogastric pain last year, the number of sex work location > or =4. CONCLUSION: Vaginal douching was shown a risk factor for HIV and some STD.