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4种市售盐酸洛美沙星片剂体外溶出度的比较
引用本文:王迎春,周学琴,胡虹. 4种市售盐酸洛美沙星片剂体外溶出度的比较[J]. 安徽医药, 2004, 8(1): 50-51
作者姓名:王迎春  周学琴  胡虹
作者单位:北京大学深圳医院,深圳,518036
摘    要:目的通过测定4种市售盐酸洛美沙星片剂的溶出度,来考察产品质量.方法按中国药典2000年版采用紫外分光光度法测定盐酸洛美沙星片剂溶出度.结果4种市售盐酸洛美沙星片剂均符合中国药典2000年版标准,30 min溶出80%以上.结论为保证临床用药安全有效,应严格按照中国药典规定控制该产品的内在质量.

关 键 词:盐酸洛美沙星片  溶出度  紫外分光光度法  盐酸洛美沙星  片剂溶出度  体外溶出度  比较  in vitro  tablets  lomefloxacin hydrochloride  dissolution rate  内在质量  产品质量  控制  用药安全有效  临床  标准  结果  紫外分光光度法测定  药典  中国  方法  考察
修稿时间:2003-11-03

Study on the dissolution rate of lomefloxacin hydrochloride tablets in vitro
WANG Ying Chun,ZHOU Xue Qin,HU Hong. Study on the dissolution rate of lomefloxacin hydrochloride tablets in vitro[J]. Anhui Medical and Pharmaceutical Journal, 2004, 8(1): 50-51
Authors:WANG Ying Chun  ZHOU Xue Qin  HU Hong
Abstract:AIM To determine the dissolution of lomefloxacin hydrochloride tablets from 4 demestic plants.METHODS The dissolution were acquired according to Chinese pharmacopeia(2000)with UV spectrophotometry in vitro.RESULTS The results indicated that all the samples were dissolved in 30 minutes and dissolution rate were over 80%.CONCLUSION It is necessary to control the dissolution of lomefloxacin hydrochloride tablets.
Keywords:lomefloxacin hydrochloride tablets  dissolution  UV spectrophotometry
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