PET-CT-Bildgebung bei Kopf-Hals-Tumoren |
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Authors: | Dr Dr R Rödel H J Straehler-Pohl H Palmedo K Reichmann U Jaeger M J Reinhardt H J Biersack |
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Institution: | 1. Klinik und Poliklinik für Nuklearmedizin, Universit?tsklinikum Bonn, 4. Klinik und Poliklinik für Nuklearmedizin, Universit?tsklinikum, Sigmund-Freud-Str. 25, 53127, Bonn 3. Klinik und Poliklinik für Hals-, Nasen- und Ohrenheilkunde, Universit?tsklinikum Bonn, 2. Radiologische Klinik, Universit?tsklinikum Bonn,
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Abstract: | AIM: To evaluate the usefulness of combined PET/CT examinations for detection of malignant tumors and their metastases in head and neck oncology. METHODS: 51 patients received whole body scans on a dual modality PET/CT system. CT was performed without i.v. contrast. The results were compared concerning the diagnostic impact of native CT scan on FDG-PET images and the additional value of fused imaging. RESULTS: From 153 lesions were 97 classified as malignant on CT and 136 on FDG/PET images, as suspicious for malignancy in 33 on CT and 7 on FDG-PET and as benign in 23 on CT and 10 on FDG-PET. With combined PET/CT all primary and recurrent tumors could be found, the detection rate in patients with unknown primary tumors was 45%. Compared to PET or CT alone the sensitivity, specifity and accuracy could be significantly improved by means of combined PET/CT. CONCLUSION: Fused PET/CT imaging with F18]-FDG and native CT-scanning enables accurate diagnosis in 93% of lesions and 90% of patients with head and neck oncology. |
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