| 螺内酯治疗难治性高血压的研究进展 |
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| 引用本文： | 申庆荣,李刚.螺内酯治疗难治性高血压的研究进展[J].中国医院药学杂志,2016,36(23):2126-2130. |
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| 作者姓名： | 申庆荣 李刚 |
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| 作者单位： | 1. 广西壮族自治区人民医院, 广西 南宁 530021;
2. 广西医科大学, 广西 南宁 530021 |
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| 摘 要： | 难治性高血压一直是高血压治疗的难点，通常使用多种药物治疗仍不能达标，能引起心、脑、肾等严重靶器官损害。近年来研究发现，在原治疗基础上加用螺内酯能有效促进难治性高血压的达标，故本文就螺内酯的作用机制和临床应用进行综述。
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| 关 键 词： | 螺内酯 难治性高血压 |
| 收稿时间： | 2016-02-24 |
Research progress of treatment against resistant hypertension by spironolactone |
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| SHEN Qing-rong,LI Gang.Research progress of treatment against resistant hypertension by spironolactone[J].Chinese Journal of Hospital Pharmacy,2016,36(23):2126-2130. |
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| Authors: | SHEN Qing-rong LI Gang |
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| Institution: | 1. People's Hospital of Guangxi Zhuang Autonomous Region, Guangxi Nanning 530021, China;
2. Guangxi Medical University, Guangxi Nanning 530021, China |
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| Abstract: | Resistant hypertension is difficult to be cured, though many drugs have been developed. Moreover, antihypertensive drugs can cause many adverse drug reactions and damage organs such as heart, brain, kidney, etc.. In recent years, it is found that spironolactone added into basic therapeutic regimen can effectively improve therapeutic effects of resistant hypertension. Therefore, this paper summarizes mechanism and rational use of spironolactone in literatures. |
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| Keywords: | spironolactone resistant hypertension |
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