Abstract: | Objective To investigate the clinical value of evidence-based examination of medical principles under the guidance of a number of detection performance in the identification of pleural effusion. Methods Serum and chemiluminescence immunoassay, optical assay, solid phase enzyme immunoassay, skin test method and blood sedimentation method was used to international standards that were diagnosed with lung cancer, tuberculosis, pleural effusion, pulmonary infection in 100 patients pleural effusion simultaneous CEA, CA199, CF211, NSE, SCCAg, LDH, ADA, PPD, TBAb-IgG, ESR and other 10 test. Results The tumor markers and LDH: lung cancer group were significantly higher than tuberculosis and infection, pleural effusion there are significant differences (P<0.05); ADA: The positive rate of 92% of tuberculosis, lung cancer and infection group were normal; PPD: TB -positive group was 62% , the infected group was 50%, lung cancer group was 19.2%; TBAb-IgG: TB group was 4%, while the lung cancer group and infection group were negative; ESR increased rate: tuberculosis group 94% of lung cancer group was 84.6, the infected group was 83.3% . Conclusion Under the guidance of the principles of evidence-based laboratory medicine, diagnostic tests with the eigenvalues of cancer, tuberculosi, inflammation of the pleural effusions make an objective evaluation and provide the basis for the clinician to select pilot projects. Pleural effusion detection of tumor marker levels and activity of the sensitivity, specificity is significantly higher than the serum used to identify three kinds of fluid nature of the more valuable. |